Evidence map›Paper›PMID 41809866›Full record

ArticleERJ open research2026

Effect of short-term supplemental oxygen therapy on 6-min walk distance in highlanders at risk for pulmonary hypertension: a randomised, crossover trial.

Dinah Hertig, Michael Furian, Julian Müller, Laura Mayer, Anna Titz, Mona Lichtblau, Alina Häfliger, Lena Reimann, Alessandro Vella, Maamed Mademilov and 5 more

Abstract read
In one paragraph

Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Dinah HertigDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0001-7809-3065
Michael FurianDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-8518-5029
Julian MüllerDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-4059-5937
Laura MayerDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0009-0004-4949-8548
Anna TitzDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0001-7431-1643
Mona LichtblauDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-4485-1758
Alina HäfligerDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
Lena ReimannDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
Alessandro VellaDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
Maamed MademilovDepartment of Respiratory Medicine, National Center of Cardiology and Internal Medicine, Bishkek, Kyrgyzstan.
Adilet OmuralievaDepartment of Respiratory Medicine, National Center of Cardiology and Internal Medicine, Bishkek, Kyrgyzstan.
Kay von GrünigenDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
Simon R SchneiderDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-3635-0515
Talant SooronbaevDepartment of Respiratory Medicine, National Center of Cardiology and Internal Medicine, Bishkek, Kyrgyzstan.
Silvia UlrichDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-5250-5022

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Little is known about the effects of portable supplemental oxygen therapy (SOT) to improve exercise performance in highlanders at risk for high-altitude pulmonary hypertension (HAPH). We aimed to investigate whether SOT improves the 6-min walk distance (6MWD) and reduces perceived dyspnoea in highlanders at risk for HAPH. Methods: In a pragmatic randomised open-label crossover trial, adult highlanders, living >2500 m, with a peak tricuspid regurgitation velocity >2.8 m·s Results: 47 highlanders (44% male, mean±sd age of 52±12 years, TRPG of 41±10 mmHg and oxygen saturation ( Conclusion: In hypoxaemic highlanders at risk for HAPH, portable low-dose SOT did not improve 6MWD, despite lower dyspnoea perception, lower heart rates and higher

Identifiers

PMID41809866
PMCPMC12969681

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.