ReviewTranslational andrology and urology2026
Holmium laser enucleation of the prostate (HoLEP): a narrative review of sexual side effects.
Review in Translational andrology and urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objective: Benign prostatic hyperplasia (BPH) is one of the most prevalent urological conditions. Holmium laser enucleation of the prostate (HoLEP) has emerged as a durable, effective, and minimally invasive treatment option for men with BPH. Despite the success of HoLEP in men with BPH, it is not without postoperative side effects, both sexual and non-sexual. This narrative review compiles existing evidence of side effects associated with HoLEP. The review mostly covers sexual side effects but also discusses some non-sexual side effects. There can be significant overlap between sexual and non-sexual side effects; thus, both were included. Methods: A search of the medical literature was carried out in PubMed and Medline, focusing on original research and systematic reviews on HoLEP and its sexual side effects. Key Content and Findings: Due to the nature of BPH and HoLEP, sexual side effects are significant considerations in patients undergoing HoLEP. Multiple studies have shown the commonality of retrograde ejaculation (RE) and ejaculatory dysfunction after HoLEP. Other studies have shown some effect on the orgasm itself, but overall unchanged sexual satisfaction. Conclusions: HoLEP is a durable, effective, and safe option for men with BPH. It has high rates of RE, which can affect sexual health and orgasmic function. However, the effects typically are not largely impactful to the overall sexual health and satisfaction of men.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.