ArticleTranslational andrology and urology2026
Homozygous
Article in Translational andrology and urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Teratozoospermia, characterized by a high proportion of morphologically abnormal sperm, severely impairs male fertility. This study focused on an infertile male patient presenting with globozoospermia and multiple morphological abnormalities of the flagella (MMAF), with the aim of uncovering the etiology of teratozoospermia. Methods: An infertile male patient presenting with globozoospermia and MMAF was enrolled in this study. Whole-exome sequencing (WES) was performed to screen for potential pathogenic genetic variants associated with teratozoospermia. Immunofluorescence (IF) staining was subsequently employed to examine the expression patterns. Subsequently, IF staining was conducted to evaluate the expression patterns of unconventional myosin VIIa (Myo7a) and assess acrosome integrity in sperm cells. Additionally, western blot (WB) and co-immunoprecipitation (Co-IP) were adopted to investigate potential molecular disruptions in spermatogenesis pathways. Finally, intracytoplasmic sperm injection (ICSI) and artificial oocyte activation (AOA) were performed, followed by embryo transfer to evaluate the efficacy of assisted reproductive technology in this specific pathological context. Results: Genetic screening via WES identified a homozygous Conclusions: Our findings indicate that
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.