ArticleBrazilian journal of veterinary medicine2026
Electrochemotherapy in the treatment of maxillary multilobular bone tumor in a dog: clinical, histopathological, and tomographic findings.
Article in Brazilian journal of veterinary medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Multilobular Bone Tumor (MBT) is a rare, slow-growing, and locally invasive neoplasm in middle-aged to older dogs, occurring predominantly in flat bones of the skull, pelvis, or ribs. This work reports the case of a 10-year-old, castrated, male Schnauzer, presenting with a tumorous growth in the incisor region measuring 1.0 x 0.7 x 0.6 centimeters for 30 days. Excisional biopsy revealed polygonal, hyperchromatic mesenchymal cells with oval nuclei and condensed chromatin, confirming a well-differentiated MLTB. However, the tumor recurred within 5 months, measuring 3.3 x 2.4 centimeters in the same region. Computed tomography (CT) revealed a mixed bone reaction, predominantly lytic, involving the incisive bone at the level of the incisor and canine teeth. The owner declined rostral maxillectomy and opted for a palliative approach with electrochemotherapy (bleomycin 15,000 UI/m
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