Evidence map›Paper›PMID 41809606›Full record

SynthesisSultan Qaboos University medical journal2026

Thoracic Aorta Calcification and Risk of All-Cause Mortality and Cardiovascular Outcomes:

Yasir Salah Jumah Alam, Hussein Nafakhi, Alaa Salah Jumaah, Akeel Abed Yasseen, Zahraa Alaa Salah Alam, Ali Athir Abdulraheem

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Sultan Qaboos University medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yasir Salah Jumah AlamDepartment of Internal Medicine, Faculty of Medicine, University of Kufa, Kufa, Iraq.ORCID 0000-0001-7913-3727
Hussein NafakhiDepartment of Internal Medicine, Faculty of Medicine, University of Kufa, Kufa, Iraq.ORCID 0000-0002-0238-0460
Alaa Salah JumaahDepartment of Pathology and Forensic Medicine, Faculty of Medicine, University of Kufa, Kufa, Iraq.ORCID 0000-0001-9709-1460
Akeel Abed YasseenDepartment of Pathology and Forensic Medicine, Faculty of Medicine, University of Kufa, Kufa, Iraq.ORCID 0000-0001-5050-4408
Zahraa Alaa Salah AlamDepartment of Pathology and Forensic Medicine, Faculty of Medicine, University of Kufa, Kufa, Iraq.ORCID 0009-0004-8922-9940
Ali Athir AbdulraheemDepartment of Pathology and Forensic Medicine, Faculty of Medicine, University of Kufa, Kufa, Iraq.ORCID 0009-0007-6552-458

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review aimed to assess thoracic aorta calcification (TAC) as a predictor of all-cause mortality, cardiovascular (CV) morbidity and mortality across various clinical settings using different imaging modalities. Medical databases were systematically searched up to mid-July 2025 for studies linking TAC with mortality and CV outcomes. A total of 43 studies involving 176,738 participants were included. TAC was associated with higher risks of all-cause mortality (hazard ratio [HR] = 1.614), CV mortality (HR = 2.130), coronary events (HR = 1.423), major adverse cardiac events (HR = 2.011) and stroke (HR = 1.450. Computed tomography showed the strongest associations (all-cause mortality HR = 1.810; CV mortality HR = 2.641), followed by chest radiography and echocardiography. Mortality risk was elevated across all aortic segments, including descending aorta (HR = 1.414), aortic arch (HR = 1.362), ascending aorta (HR = 1.350) and aortic root (HR = 1.240). TAC is a strong predictor of all-cause mortality, coronary events, CV mortality and morbidity.

Indexed as

Aorta, ThoracicAortic DiseasesCardiovascular DiseasesVascular CalcificationHumansRisk FactorsAortaMorbidityMortalityPrognosisThoracic

Identifiers

PMID41809606
PMCPMC12969457

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.