Evidence map›Paper›PMID 41809502›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Plasma p-tau217 and

Ann M Stowe, Bilal Kahn, Ali Ballesteros, Monique Cortez, Linda S Hynan, Victoria Cantrell, Indu Raman, Guangchun Chen, Eric D Vidoni, Ellen Binder and 11 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Plasma p-tau217 andAlzheimer's & dementia (Amsterdam, Netherlands)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Ann M StoweDepartment of Neurology University of Kentucky Lexington Kentucky USA.ORCID https://orcid.org/0000-0001-8111-4429
Bilal KahnDepartment of Psychiatry University of Texas Southwestern Medical Center Dallas Texas USA.
Ali BallesterosDepartment of Psychiatry University of Texas Southwestern Medical Center Dallas Texas USA.
Monique CortezDepartment of Psychiatry University of Texas Southwestern Medical Center Dallas Texas USA.
Linda S HynanDepartment of Psychiatry University of Texas Southwestern Medical Center Dallas Texas USA.
Victoria CantrellDepartment of Psychiatry University of Texas Southwestern Medical Center Dallas Texas USA.
Indu RamanDepartment of Immunology University of Texas Southwestern Medical Center Dallas Texas USA.
Guangchun ChenDepartment of Immunology University of Texas Southwestern Medical Center Dallas Texas USA.
Eric D VidoniAlzheimer's Disease Research Center University of Kansas Lawrence Kansas USA.
Ellen BinderDivision of General Medicine and Geriatrics Washington University St. Louis Missouri USA.
Jeffrey BurnsAlzheimer's Disease Research Center University of Kansas Lawrence Kansas USA.
Jeffrey N KellerInstitute for Dementia Research & Prevention Pennington Biomedical Research Center Louisiana State University Baton Rouge Louisiana USA.
Diana R KerwinKerwin Medical Center and Chief of Geriatrics Texas Health Presbyterian Hospital Dallas Texas USA.
Tristyn HallTexas Health Presbyterian Hospital Dallas Texas USA.
Pavel YanevDepartment of Neurology University of Kentucky Lexington Kentucky USA.
Wanpen VongpatanasinDepartment of Internal Medicine University of Texas Southwestern Medical Center Dallas Texas USA.
David C ZhuDepartment of Radiology and Gruss Magnetic Resonance Research Center Albert Einstein College of Medicine New York New York USA.
Norman ScheelDepartment of Radiology Michigan State University East Lansing Michigan USA.
C Munro CullumDepartment of Psychiatry University of Texas Southwestern Medical Center Dallas Texas USA.
Rong ZhangKerwin Medical Center and Chief of Geriatrics Texas Health Presbyterian Hospital Dallas Texas USA.
Dwight C GermanDepartment of Psychiatry University of Texas Southwestern Medical Center Dallas Texas USA.

Funding

Exercise and Intensive Vascular Risk Reduction in Preventing DementiaR01AG049749 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI BINDER, ELLEN F, BURNS, JEFFREY MURRAY · 2016 to 2020
$15.1M
Diversity Supplement for Jenny LutshumbaRF1AG084134 · NIA · UNIVERSITY OF KENTUCKY · PI GERMAN, DWIGHT C., STOWE, ANN MARIE · 2023 to 2024
$2.6M
Biomarkers to Track Effective Interventions that Delay Dementia Onset in Participants of the "Risk Reduction for Alzheimer's Disease (rrAD)" TrialR01AG084134 · NIA · UNIVERSITY OF KENTUCKY · PI DWIGHT C. German, Ann Marie Stowe · 2026 to 2026
$742k
Biomarkers to track effective interventions that delay dementia onset in participants of the "Risk Reduction for Alzheimer's Disease (rrAD)" trialR56AG074613 · NIA · UNIVERSITY OF KENTUCKY · PI GERMAN, DWIGHT C., STOWE, ANN MARIE · 2021 to 2021
$715k
NIA NIH HHS R01 AG049749NIA NIH HHS R01 AG084134NIA NIH HHS R56 AG074613NIA NIH HHS RF1 AG084134
6 · The paper itself

Abstract

Introduction: Plasma phosphorylated tau (p-tau)217 levels and apolipoprotein E ( Methods: We measured Results: Plasma p-tau217 was 57% higher in subjects with at least one Discussion: Plasma p-tau217 demonstrated elevation in the

Indexed as

Alzheimer's disease riskapolipoprotein E genotypecardiovascular risk factorsdementiaphosphorylated au217 plasma biomarker

Identifiers

PMID41809502
PMCPMC12968440

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.