Evidence map›Paper›PMID 41809482›Full record

ArticleWorld journal of hepatology2026

Advances in biliary stone management: Latest-generation extracorporeal shock wave lithotripsy

Neeraj Singla, Katrevula Anudeep Venkata, Pradev Inavolu, Sana Fathima Memon, Krithi Krishna Koduri, Aniruddha Pratap Singh, Thejesh Katamareddy, Santosh Darisetty, Vinod Koppoju, Nitin Jagtap and 5 more

Abstract read
In one paragraph

Article in World journal of hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Neeraj SinglaMedical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Katrevula Anudeep VenkataMedical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Pradev InavoluMedical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India. dr.inavolup@aighospitals.com.
Sana Fathima MemonDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Krithi Krishna KoduriMedical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Aniruddha Pratap SinghMedical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Thejesh KatamareddyDepartment of Anesthesia, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Santosh DarisettyDepartment of Anesthesia, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Vinod KoppojuDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Nitin JagtapMedical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Rakesh KalpalaMedical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Sundeep LakhtakiaMedical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Mohan RamchandaniMedical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Manu TandanMedical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.
Duvvur Nageshwar ReddyMedical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangāna, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtracorporeal shock wave lithotripsy (ESWL) and laser lithotripsy (LL) are established alternatives for the management of difficult common bile duct (CBD) stones. However, there is limited evidence regarding the efficacy and safety of the latest-generation Dornier Delta III lithotripter. In particular, evidence on the clinical performance of the Dornier Delta III lithotripter is scarce.

aimTo evaluate and compare the efficacy and safety of ESWL performed with the Dornier Delta III and of LL using a single-operator cholangioscope with specific focus on stone clearance rates, number of treatment sessions, and procedure-related adverse events in a large patient cohort.

methodsWe conducted a retrospective analysis of a prospectively maintained database at AIG Hospitals, Hyderabad, covering the period from January 2019 to December 2022. A total of 458 patients with difficult bile duct stones underwent either ESWL or LL based on clinical discretion. ESWL was performed using the Dornier Delta III lithotripter, whereas LL was carried out with a single-operator cholangioscope in combination with an yttrium-aluminum-garnet laser.

resultsThe 387 patients with difficult bile duct stones (mean age 53.8 ± 15.7 years, 58.7% male) underwent ESWL. A single CBD stone was noted in 46.8% of patients while 53.2% patients had multiple stones. Complete duct clearance was achieved in 95.1% of patients, with 68.7% requiring two or more ESWL sessions. Adverse events included cholangitis in 3 patients and post-sphincterotomy bleeding in 4 patients; All were managed conservatively. Seventy-one patients (mean age 55 ± 15.4 years, 64.8% male) underwent LL. Complete duct clearance was achieved in 97.2% of patients with single-session clearance in 58 (81.7%) patients. The remaining 18.3% of patients required two or three sessions for fragmented stone removal. Adverse events included cholangitis in 2 patients and mild pancreatitis in 1 patient; all were managed conservatively. Patients with incomplete clearance were referred for surgery. There was no significant difference in efficacy between ESWL and LL (95.1%

conclusionESWL using the latest generation lithotripter and LL provide equally effective and safe alternatives for managing difficult CBD stones, minimizing the need for surgery.

Indexed as

CholedocholithiasisDifficult bile duct stoneEndoscopic retrograde cholangiopancreatographyExtracorporeal shock wave lithotripsyLaser lithotripsy

Identifiers

PMID41809482
PMCPMC12968673

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