Evidence map›Paper›PMID 41809462›Full record

ArticleBJA open2026

Effect of exercise prehabilitation on days alive and out of hospital after cardiac surgery: a secondary analysis of the randomised PRE-habilitation for improving QUality of recovery after ELective cardiac surgery trial.

Vivian N M Lau, Derek K W Yau, Floria F Ng, Vicki W S Li, Kelly K H Wong, Christina H L Wong, Pik Yi Hou, Kwok Ming Ho, Anna Lee

Abstract read
In one paragraph

Article in BJA open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vivian N M LauDepartment of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Derek K W YauDepartment of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Floria F NgDepartment of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Vicki W S LiDepartment of Anaesthesia, Pain and Perioperative Medicine, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
Kelly K H WongDepartment of Anaesthesia, Pain and Perioperative Medicine, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
Christina H L WongDepartment of Anaesthesia, Pain and Perioperative Medicine, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
Pik Yi HouDepartment of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Kwok Ming HoDepartment of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Anna LeeDepartment of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Postoperative healthcare utilisation and long-term survival are rarely evaluated after prehabilitation, limiting understanding of its sustained benefits. We investigated whether exercise-based prehabilitation improves percent days alive and out of hospital, a composite measure integrating recurrent hospitalisations and survival after cardiac surgery. Methods: This secondary exploratory analysis included participants with very mild to moderate frailty from the PREhabilitation for improving QUality of recovery after ELective cardiac surgery (PREQUEL) RCT. The trial time period was from 2018 to 2023 with follow-up continued until 31 December 2024, with readmissions and vital status retrospectively obtained from electronic medical records. One-inflated beta regression, negative binomial regressions, and restricted mean survival time analysis were used to estimate the effects of prehabilitation on %DAOH days alive out of hospital, cumulative hospital bed days owing to readmissions, and survival, respectively. Results: Among 136 participants (58 prehabilitation, 78 usual care), 94 (69.1%) were male, with a median age of 64 yr (IQR 59-69). Thirty-five (60.3%) prehabilitation and 52 (66.7%) usual care participants accounted for 119 and 165 readmissions, respectively. Prehabilitation was associated with a higher %DOAH days alive out of hospital in the unadjusted analysis (87.7% Conclusions: Exercise-based prehabilitation had little or no effect on long-term time spent at home but may confer a modest survival benefit, warranting further investigation in larger trials.

Indexed as

cardiac surgical proceduresexercise therapyfrailtypatient readmissionpreoperative caresurvival analysis

Identifiers

PMID41809462
PMCPMC12969346

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.