Evidence map›Paper›PMID 41809443›Full record

ArticleFrontiers in dental medicine2026

Fibronectin-gelatin nanofilm coating improves dental pulp stem cell survival and differentiation in odontogenesis-mimicking organotypic 3D bilayered constructs.

Alexandra Jimenez-Armijo, Isaac Maximiliano Bugueno, Fadi Jerbaka, Eve Suss, Gaétan Caravello, Marzena Kawczynski, Youri Arntz, Agnès Bloch-Zupan, Varvara Gribova

Abstract read
In one paragraph

Article in Frontiers in dental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexandra Jimenez-ArmijoInstitut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, Illkirch, France.
Isaac Maximiliano BuguenoInstitut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, Illkirch, France.
Fadi JerbakaInstitut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, Illkirch, France.
Eve SussInstitut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, Illkirch, France.
Gaétan CaravelloCentre de Référence des Maladies Rares Orales et Dentaires, CRMR-O-Rares, Hôpitaux Universitaires de Strasbourg (HUS), Filière de Santé TETECOU, ERN CRANIO, Strasbourg, France.
Marzena KawczynskiInstitut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, Illkirch, France.
Youri ArntzFaculté de Chirurgie Dentaire, Université de Strasbourg, Strasbourg, France.
Agnès Bloch-ZupanInstitut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, Illkirch, France.
Varvara GribovaInstitut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, Illkirch, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthcare professionals, researchers, patients and their families affected by rare diseases face many difficulties during diagnosis. A targeted diagnostic tool, using high-throughput sequencing (NGS) technologies, known as GenoDENT, used to unravel molecular diagnosis behind rare diseases with oral and dental manifestations, enabled the identification of more than 15% of variants of unknown significance (Class III - VUS), beside a high 70%-80% diagnostic rate in the analyzed patients' cohort. VUS make diagnosis more difficult because they prevent precise correlation between genotype and phenotype. To overcome this issue, we are developing 3D

Indexed as

3D modelsextracellular matrixlayer-by-layerodontogenesisrare diseases

Identifiers

PMID41809443
PMCPMC12968307

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.