Evidence map›Paper›PMID 41809211›Full record

ArticleWorld journal of gastrointestinal pharmacology and therapeutics2026

Fully covered metal biliary stents confer a higher risk of post-endoscopic retrograde cholangiopancreatography pancreatitis.

Linda Yun Zhang, Dhanashree Tikhe, Apurva Shrigiriwar, George Ermerak, Hsing Hwa Lee, Letisia Sin, Ian Turner, Paul Edwards, David Abi-Hanna, Luke Hourigan and 2 more

Abstract read
In one paragraph

Article in World journal of gastrointestinal pharmacology and therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Linda Yun ZhangDepartment of Gastroenterology and Hepatology, Liverpool Hospital, Liverpool 2170, New South Wales, Australia.
Dhanashree TikheDepartment of Gastroenterology and Hepatology, Liverpool Hospital, Liverpool 2170, New South Wales, Australia.
Apurva ShrigiriwarDepartment of Gastroenterology and Hepatology, Johns Hopkins Medical Institutions, Baltimore, MD 21231, United States.
George ErmerakDepartment of Gastroenterology and Hepatology, Liverpool Hospital, Liverpool 2170, New South Wales, Australia.
Hsing Hwa LeeDepartment of Gastroenterology and Hepatology, Princess Alexandra Hospital, Woolloongabba 4102, Queensland, Australia.
Letisia SinDepartment of Gastroenterology and Hepatology, Port Macquarie Base Hospital, Port Macquarie 2444, New South Wales, Australia.
Ian TurnerDepartment of Gastroenterology and Hepatology, Liverpool Hospital, Liverpool 2170, New South Wales, Australia.
Paul EdwardsDepartment of Gastroenterology and Hepatology, Liverpool Hospital, Liverpool 2170, New South Wales, Australia.
David Abi-HannaDepartment of Gastroenterology and Hepatology, Liverpool Hospital, Liverpool 2170, New South Wales, Australia.
Luke HouriganDepartment of Gastroenterology and Hepatology, Princess Alexandra Hospital, Woolloongabba 4102, Queensland, Australia.
Stuart KostalasDepartment of Gastroenterology and Hepatology, Port Macquarie Base Hospital, Port Macquarie 2444, New South Wales, Australia.
Milan BassanDepartment of Gastroenterology and Hepatology, Liverpool Hospital, Liverpool 2170, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBiliary fully-covered self-expanding metal stents (FCSEMS) are increasingly used over plastic or uncovered SEMS due to their long-term patency and removability. However, there is concern that transpapillary placement may lead to post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).

aimTo assess the rates of PEP with and without the use of FCSEMS for both benign and malignant indications.

methodsWe performed a multicenter retrospective cohort study involving three Australian tertiary referral centers. Consecutive adults who underwent ERCP for biliary indications between October 2016 and October 2019 were included. The primary endpoint was the rate of PEP. Secondary endpoints included severity of pancreatitis, other procedure- and stent-related adverse events occurring within 90 days.

resultsA total of 3401 ERCPs were performed (54.2% female, mean age 62.9±18.6 years) with an overall PEP rate of 3.15%. On propensity-score matched analysis, FCSEMS was an independent predictor of PEP (odds ratio = 5.49, 95% confidence interval: 2.10-6.99;

conclusionBiliary FCSEMS are associated with a higher risk of PEP compared to no stents or plastic stents, particularly for benign indications.

Indexed as

Endoscopic retrograde cholangiopancreatogramFully-covered self-expanding metal stentsMetal biliary stentPancreatitisPlastic biliary stent

Identifiers

PMID41809211
PMCPMC12968636

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.