ArticleWorld journal of gastrointestinal pharmacology and therapeutics2026
Endoscopic ultrasound-guided pancreatic pseudocyst drainage in pediatric patients.
Article in World journal of gastrointestinal pharmacology and therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPancreatic pseudocyst (PPC) is a well-encapsulated peri-pancreatic fluid collection that occurs at least 4 weeks after acute pancreatitis. The prevalence of PPC is 8%-41% among patients with a history of pancreatitis. Management includes conventional surgery and percutaneous radiological or endoscopic approaches. Endoscopic ultrasound (EUS)-guided drainage of PPC appears to be a safe and less invasive treatment option. Its efficacy is well established in the adult population. However, data regarding its usage in the pediatric population are limited.
aimTo determine the safety and efficacy of EUS-guided PPC drainage in children over 10 years.
methodsA retrospective review was conducted of pediatric patients (aged < 18 years) who were referred for EUS-guided PPC drainage between 2015 and 2024. Twenty-eight patients were identified who had been referred to our department for EUS-guided PPC drainage, including 21 patients with symptoms who underwent the procedure. Effectiveness was assessed based on technical success and clinical resolution of symptoms.
resultsThe mean age was 13.81 ± 3.25 years (range: 6-18 years) with 52.4% males. The locations of the PPCs were distributed along the pancreatic body (38.1%) and head/neck regions (38.1%). EUS-guided drainage was performed under general anesthesia. Complete aspiration without stent placement was performed in 11 patients (52.4%) with an average PPC size of 4.3 cm × 3.9 cm. Two double-pigtail plastic stents were required in 9 patients (47.6%) with a mean size of 8.4 cm × 8.0 cm. Lumen-apposing metal stents were required in 1 patient. Technical and clinical successes were achieved in all cases. One patient (4.8%) experienced recurrence that required repeat drainage. No major complications were observed.
conclusionEUS-guided PPC drainage was a safe and effective procedure for our pediatric population and should be preferred over conventional techniques, performed by experienced endoscopists under general anesthesia by pediatric anesthetists.
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