Evidence map›Paper›PMID 41809169›Full record

ArticleWorld journal of methodology2026

Multiparametric magnetic resonance imaging in differentiating benign and malignant sinonasal masses: A prospective study and literature review.

Manish Saini, Smita Manchanda, Ashu S Bhalla, Devasenathipathy Kandasamy, Aanchal Kakkar, Alok Thakar

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Article in World journal of methodology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Manish SainiDepartment of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi 110029, India.
Smita ManchandaDepartment of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi 110029, India. smitamanchanda@gmail.com.
Ashu S BhallaDepartment of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi 110029, India.
Devasenathipathy KandasamyDepartment of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi 110029, India.
Aanchal KakkarDepartment of Pathology, All India Institute of Medical Sciences, New Delhi 110029, India.
Alok ThakarDepartment of Otorhinolaryngology and Skull Base Surgery, All India Institute of Medical Sciences, New Delhi 110029, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe sinonasal area poses diagnostic challenges due to a range of benign and malignant tumors presenting with vague symptoms. Conventional magnetic resonance imaging (MRI) has limited specificity in differentiation.

aimTo study the role of dynamic contrast-enhanced MRI (DCE-MRI), intravoxel incoherent motion imaging (IVIM), diffusion kurtosis imaging (DKI), and conventional diffusion-weighted imaging (DWI) for distinguishing between benign and malignant sinonasal masses.

methodsThis prospective study was conducted at a tertiary center in which 30 patients with sinonasal masses (18 malignant lesions and 12 benign lesions) underwent routine MRI, conventional DWI and IVIM, and DCE-MRI. Various imaging parameters were measured and compared between two groups.

resultsMalignant lesions exhibited significantly lower apparent diffusion coefficient (ADC), true diffusion coefficient (Dt), and apparent diffusion coefficient (Dapp) values (

conclusionThis study highlights the utility of conventional DWI, DKI, and IVIM as noninvasive methods for distinguishing between benign and malignant sinonasal lesions; however, there is no added advantage of DKI and IVIM over conventional DWI. Similarly, the perfusion parameters also did not show an additive role in distinguishing between benign and malignant sinonasal lesions.

Indexed as

BenignDiffusion kurtosis imagingDiffusion-weighted imagingDynamic contrast-enhanced imagingIntravoxel incoherent motion imagingMagnetic resonance imagingMalignantSinonasal masses

Identifiers

PMID41809169
PMCPMC12968767

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