ArticleWorld journal of methodology2026
Apparent diffusion coefficient of kidneys with non-contrast magnetic resonance angiography for functional and anatomical assessment in renal artery stenosis.
Article in World journal of methodology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundRenal artery stenosis (RAS) is a vascular disorder linked to secondary hypertension, chronic kidney disease, and renal failure due to interstitial fibrosis. Early diagnosis is crucial as RAS-induced hypertension responds well to angioplasty. Non-invasive imaging techniques, including non-contrast magnetic resonance angiography (NC-MRA), help assess RAS without contrast-related risks. Diffusion-weighted MR imaging (DW-MRI) has emerged as a promising method for evaluating kidney function by measuring the apparent diffusion coefficient (ADC), which correlates with renal pathology.
aimTo compare ADC values in hypertensive, RAS, and healthy kidneys, assess the correlation between ADC and stenosis severity, and evaluate its relationship with split glomerular filtration rate (GFR).
methodsThis prospective observational study which included 86 patients with suspected RAS and twenty normal healthy controls underwent NC-MRA on a 3T-MR-Scanner followed by DW-MRI at b values of 0 and 1000 seconds/mm
resultsRAS was detected in 58 of 86 (67.44%) hypertensive patients (81 of 172 kidneys), and the ADCavg (
conclusionDW-MRI can be a useful non-invasive technique to estimate the kidney's functional status in RAS patients. It can be used as a complementary assessment tool with NC-MRA to triage patients in need of interventional management.
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