Evidence map›Paper›PMID 41809147›Full record

ArticleSouthern African journal of HIV medicine2026

Barriers and facilitators of ongoing engagement in substance use treatment programmes among people with HIV in South Africa: A qualitative analysis.

Thanusha Pillay, Stefani Du Toit, Chiara Sforza, Abigail Hines, Alexandra Rose, Jessica Magidson, John Joska

Abstract read
In one paragraph

Article in Southern African journal of HIV medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thanusha PillayDepartment of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0009-0008-1131-4968
Stefani Du ToitHIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-7947-3043
Chiara SforzaDepartment of Psychology, University of Maryland, College Park, Maryland, United States.ORCID https://orcid.org/0009-0008-7447-9401
Abigail HinesThe Global Mental Health and Addiction Program, University of Maryland, College Park, Maryland, United States.ORCID https://orcid.org/0000-0001-8485-6903
Alexandra RoseDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, United States.ORCID https://orcid.org/0000-0001-9689-0834
Jessica MagidsonDepartment of Psychology, Center for Substance Use, Addiction and Health Research, University of Maryland, College Park, Maryland, United States.ORCID https://orcid.org/0000-0002-3513-3255
John JoskaHIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-4260-1181

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: South Africa has a high prevalence of HIV and substance use, with 13% of the population meeting criteria for lifetime substance use disorder (SUD). Substance disorders are associated with adverse health outcomes, including poor adherence to antiretroviral therapy (ART), reduced health-seeking behaviour and increased risk-taking behaviour. Limited research has explored the perspectives of people with HIV in low- and middle-income countries when accessing substance use treatment. Objectives: To identify barriers and facilitators influencing engagement in substance use treatment programmes among people with HIV and SUDs, drawing on perspectives from both patients and healthcare providers. Method: This qualitative study analysed individual interviews from Project Khanya, a peer-delivered intervention promoting ART adherence among adults living with HIV with at least a moderate SUD. Using criterion sampling, 34 adults with HIV and nine healthcare providers involved in HIV or substance use care were included. Inductive thematic analysis of transcripts from audio recordings identified individual, social, and structural factors influencing treatment engagement. Results: Participants had a mean age of 39.2 years and 48% were female; providers had a mean age of 40.8 years and were predominantly female. Five main subthemes influenced engagement in substance use treatment: social support, substance use, service-related factors, readiness to change, and financial constraints. Facilitators included strong social support, positive healthcare experiences, outreach, psychoeducation, insight, and reduced substance use, while barriers included poor support, stigma, negative healthcare interactions, financial challenges, and ongoing substance use. Conclusion: Intersectional stigma, privacy concerns, and ongoing substance use hinder engagement in HIV and SUD treatment, whereas holistic, person-centred approaches can improve programme attendance and health outcomes.

Indexed as

HIVqualitative researchSouth Africasubstance usetreatment engagement

Identifiers

PMID41809147
PMCPMC12969580

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.