ArticleIEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
Unified Vibrational and Multiphoton Label-Free Nonlinear Microscopy for Simultaneous Chemical and Structural Imaging.
Article in IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Label-free multimodal nonlinear microscopy enabled by an optical parametric generator.APL photonics · 2026Article
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Abstract
Nonlinear microscopy enables label-free imaging by deriving contrast from the intrinsic spectroscopic responses of specimens, thereby offering a valuable tool for biomedical applications. Often, clinical imaging systems implement either multiphoton or vibrational contrast, not both. Consequently, most clinically deployed label-free nonlinear microscopes lack a robust, complementary contrast palette suitable for investigating the morphofunctional features of heterogeneous specimens. This deficiency limits not only the analytical capabilities of the nonlinear microscope but also its diagnostic utility. A main reason for this disregard is that the various imaging modalities impose distinct and stringent requirements on the excitation source and the detection chain. In this contribution, we propose a strategy that targets
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