Evidence map›Paper›PMID 41808992›Full record

ArticlebioRxiv : the preprint server for biology2026

Comprehensive top-down mass spectral repository enables pan-dataset analysis and top-down spectral prediction.

Kun Li, Kaiyuan Liu, James M Fulcher, Philipp T Kaulich, Haixu Tang, Xiaowen Liu

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kun LiDeming Department of Medicine, School of Medicine, Tulane University, New Orleans, Louisiana, 70112, USA.
Kaiyuan LiuLuddy School of Informatics, Computing, and Engineering, Indiana University Bloomington, Indiana, 47405, USA.
James M FulcherEnvironmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, 99354, USA.ORCID 0000-0001-9033-3623
Philipp T KaulichSystematic Proteome Research & Bioanalytics, Institute for Experimental Medicine, Christian-Albrechts-Universität zu Kiel, Kiel, Germany.
Haixu TangLuddy School of Informatics, Computing, and Engineering, Indiana University Bloomington, Indiana, 47405, USA.ORCID 0000-0001-8963-8155
Xiaowen LiuDeming Department of Medicine, School of Medicine, Tulane University, New Orleans, Louisiana, 70112, USA.ORCID 0000-0003-4139-1127

Funding

Quantitative Characterization of Glycopeptide IsomersR01GM130091 · NIGMS · TEXAS TECH UNIVERSITY · PI Yehia Mechref · 2019 to 2026
$2.5M
Quantitative top-down proteomics of human colorectal cancer cells and tumorsR01CA247863 · NCI · MICHIGAN STATE UNIVERSITY · PI HUMMON, AMANDA B., LIU, XIAOWEN · 2021 to 2025
$1.9M
Spatially resolved characterization of proteoforms for functional proteomicsUG3CA256959 · NCI · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI PASA-TOLIC, LJILJANA · 2020 to 2021
$600k
NCI NIH HHS R01 CA247863NCI NIH HHS UG3 CA256959NIGMS NIH HHS R01 GM130091
6 · The paper itself

Abstract

Mass spectral libraries have become essential resources for training deep learning (DL) models for spectral prediction and

Identifiers

PMID41808992
PMCPMC12970328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.