ArticleJournal of neurological surgery. Part B, Skull base2026
Individual and Community-Level Social Determinant Associations with Skull Base Chordoma and Chondrosarcoma Disparities in the United States.
Article in Journal of neurological surgery. Part B, Skull base, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Objective: Using multivariate models of social determinants of health (SDoH) featuring census-level Yost Index-socioeconomic status (SES) measures, to determine whether community-level SDoH factors quantifiably influence skull base chordoma-chondrosarcoma disparities more than individual-level SDoH factors on care-prognostic differences nationally. Design Setting Participants: Retrospective cohort, skull base chordomas/chondrosarcoma patients diagnosed between 2010 and 2018 from SEER (Surveillance, Epidemiology, and End Results) were analyzed by multivariate, age-adjusted regressions and Cox proportional hazards models; covariates of sex, race-ethnicity, census-level rurality-urbanicity, census-level Yost-Index score (aggregating 7 SES-measures of education, income, housing). Main Outcome Measures: Mortality, late-staging, first-line/nonfirst-line treatment, delay-in-treatment. Results: Across 1,530 skull base chordomas and chondrosarcomas, delay-of-treatment featured a markedly positive independent predictor of minority race/ethnicity (odds ratio [OR], 1.72; 95% confidence interval [CI], 1.27-1.34; Conclusion: Through interactional models of individual- and community-level social determinant factors, this study observed detrimental, interrelated SDoH associations with poorer care and prognosis of chordoma and chondrosarcoma patients while quantifiably delineating the strength of factor association with observed disparities.
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