Evidence map›Paper›PMID 41808952›Full record

ArticleCirculation reports2026

Outcomes of Thoracoscopic Left Atrial Appendage Occlusion With or Without Concomitant Thoracoscopic Ablation - Multicenter Retrospective Registry of 567 Patients in Japan.

Taisuke Nakayama, Hiroshi Ito, Shunsuke Sato, Seimei Kure, Gentaku Hama, Masakazu Aoki, Shinya Takahashi

Abstract read
In one paragraph

Article in Circulation reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Taisuke NakayamaDepartment of Cardiovascular Surgery, Chiba-Nishi General Hospital Chiba Japan.
Hiroshi ItoDepartment of Cardiovascular Surgery, Saiseikai Shimonoseki General Hospital Yamaguchi Japan.
Shunsuke SatoDepartment of Cardiovascular Surgery, Yodogawa Christian Hospital Osaka Japan.
Seimei KureDepartment of Cardiovascular Surgery, Hiroshima University Hospital Hiroshima Japan.
Gentaku HamaDepartment of Cardiovascular Surgery, Sapporo Cardio Vascular Clinic, Sapporo Heart Center Sapporo Japan.
Masakazu AokiDepartment of Cardiovascular Surgery, Matsumoto Kyouritsu Hospital Nagano Japan.
Shinya TakahashiDepartment of Cardiovascular Surgery, Hiroshima University Hospital Hiroshima Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial fibrillation (AF) is a major risk factor for ischemic stroke, with >90% of thrombi in nonvalvular AF originating in the left atrial appendage (LAA). Thoracoscopic LAA occlusion (LAAO), with or without ablation, is a minimally invasive alternative to endocardial devices or anticoagulation, but multicenter data are limited. Methods and Results: The Totally Thoracoscopic Left Atrial Appendage Occlusion Study (TT-LAAOS) is a multicenter Japanese registry of thoracoscopic LAAO in nonvalvular AF. From March 2018 to December 2024, 567 patients underwent the procedure at 6 institutions using stapler excision or epicardial clip. Outcomes included procedural success, anatomic closure, cerebrovascular events, and anticoagulant withdrawal. Mean age was 72 years; 63.5% had long-standing persistent AF. Median CHADS Conclusions: Thoracoscopic LAAO, with or without ablation, is safe and effective for stroke prevention in AF, with high success, reliable closure, and very low midterm events.

Indexed as

Atrial fibrillationLeft atrial appendageMinimally invasive cardiac surgeryStrokeTotal thoracoscopic procedure

Identifiers

PMID41808952
PMCPMC12971204

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.