Evidence map›Paper›PMID 41808949›Full record

ArticleCirculation reports2026

Pancreatic Exocrine Function in Hospitalized Patients Following Acute Decompensated Heart Failure - An Observational Cross-Sectional Study.

Masaru Hiki, Takatoshi Kasai, Akihiro Sato, Sayaki Ishiwata, Shoichiro Yatsu, Jun Shitara, Hiroki Matsumoto, Megumi Shimizu, Azusa Murata, Takao Kato and 2 more

Abstract read
In one paragraph

Article in Circulation reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Masaru HikiDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine Tokyo Japan.
Takatoshi KasaiDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine Tokyo Japan.
Akihiro SatoDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine Tokyo Japan.
Sayaki IshiwataDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine Tokyo Japan.
Shoichiro YatsuDepartment of Cardiology, Juntendo University Shizuoka Hospital Shizuoka Japan.
Jun ShitaraDepartment of Cardiology, Juntendo University Shizuoka Hospital Shizuoka Japan.
Hiroki MatsumotoDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine Tokyo Japan.
Megumi ShimizuDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine Tokyo Japan.
Azusa MurataDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine Tokyo Japan.
Takao KatoDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine Tokyo Japan.
Shoko SudaDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine Tokyo Japan.
Hiroyuki DaidaDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute decompensated heart failure (ADHF) causes multi-organ damage associated with congestion, hypoperfusion, or both. However, its impact on pancreatic exocrine function (PEF), which can be associated with impaired digestion and absorption and contribute to malnutrition, remains unclear. Thus, in this proof-of-concept study, we investigated whether hospitalized patients with ADHF have impaired PEF. Methods and Results: Patients admitted to the cardiac intensive care unit were enrolled. Following initial stabilization, the Conclusions: PEF was impaired in hospitalized patients with ADHF. Our findings could inform further hypotheses regarding how improved PEF in hospitalized patients with ADHF affects their nutritional status.

Indexed as

CongestionMulti-organ damageN-benzoyl-L-tyrosyl-p-aminobenzoic acid testPancreatic function diagnostic

Identifiers

PMID41808949
PMCPMC12971195

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.