ReviewLancet regional health. Americas2026
Precision diagnosis and therapy for pediatric central nervous system tumors: consensus from the Brazilian Society of Pediatric Oncology (SOBOPE).
Review in Lancet regional health. Americas, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Special Issue "Pediatric Diseases: From Molecular Mechanisms to Novel Therapeutic Strategies".International journal of molecular sciences · 2026Article
Corrections and comments
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Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Precision medicine has reshaped the classification and management of pediatric central nervous system tumors, enabling more accurate diagnoses and targeted therapies. However, access to molecular diagnostics and precision treatments remains uneven in many low- and middle-income countries, including Brazil. To address this gap, the Brazilian Society of Pediatric Oncology (SOBOPE) convened a national expert panel to develop consensus recommendations adapted to the Brazilian healthcare context. Using a structured literature overview and a modified Delphi process involving pediatric oncologists, neuropathologists, and laboratory medicine specialists, the panel proposed a tiered molecular testing strategy prioritizing essential and actionable biomarkers. Recommendations were tailored to both public and private healthcare settings and aligned with therapeutic guidance when targeted options are feasible. This consensus provides a practical framework to standardize molecular testing, support clinical decision-making, and promote equitable implementation of precision medicine in pediatric neuro-oncology in Brazil.
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Registered trials
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