ReviewGland surgery2026
Optimizing perioperative care in autologous breast reconstruction: a narrative review.
Review in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objective: Autologous breast reconstruction is a complex microsurgical procedure in which perioperative management critically influences surgical and patient-reported outcomes. Several physiological and perioperative strategies-including oxygenation enhancement, metabolic modulation, nutritional support and wound care-remain underexplored in this specific setting. This narrative review summarizes evidence on emerging approaches to perioperative optimization in autologous breast reconstruction and discusses their potential to improve recovery and long-term outcomes. Methods: A narrative literature review was conducted using PubMed (MEDLINE, Bethesda, MD, USA) and Scopus (Elsevier, Amsterdam, The Netherlands) for studies published in English up to October 2025. Reference lists of key reviews and consensus statements were manually screened to identify additional relevant publications. The selected literature was analyzed thematically to highlight evolving concepts and their reported impact on reconstructive outcomes. Key Content and Findings: Emerging strategies target perioperative physiology through systemic and local interventions. Hyperbaric oxygen therapy and closed-incision negative pressure wound therapy demonstrate potential benefits in improving perfusion, reducing edema, and lowering wound-related complications. Antioxidant and metabolic modulation, perioperative protein optimization, and preoperative carbohydrate loading may attenuate catabolic stress and support microvascular stability. Structured drain care and infection-prevention protocols further contribute to safer recovery. Evidence remains heterogeneous and limited in scope, but collectively these approaches point toward a more comprehensive and individualized perioperative management paradigm in reconstructive breast surgery. Conclusions: Optimizing perioperative care in autologous breast reconstruction requires an integrated framework that aligns surgical precision with systemic support. Emerging biological and metabolic interventions may complement established recovery practices, potentially improving flap outcomes and overall patient well-being. Prospective multicenter studies are needed to standardize protocols and determine their clinical impact.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.