Evidence map›Paper›PMID 41808729›Full record

Article3 Biotech2026

Molecular mechanism of anticancer activity of selected coastal marsh plants from Saudi Arabia.

Fahad Alharthi, Hussam A Althagafi, Ibrahim Jafri, Leena S Alqahtani, Hind Althagafi, Atif Abdulwahab A Oyouni, Abdullah A A Alghamdi, Abdullah M Almotayri, Fawzya AlOmari, Deyala M Naguib

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fahad AlharthiDepartment of Biology, College of Science, Taif University, PO Box 11099, Taif, 21944 Saudi Arabia.ORCID 0000-0003-3370-3899
Hussam A AlthagafiDepartment of Biology, Faculty of Science, Al-Baha University, Al-Baha, Saudi Arabia.ORCID 0000-0003-0311-2975
Ibrahim JafriDepartment of Biotechnology, College of Science, Taif University, P.O. Box 11099, Taif, 21944 Saudi Arabia.ORCID 0000-0002-8465-6829
Leena S AlqahtaniDepartment of Biological Sciences, College of Science, University of Jeddah, Jeddah, 23445 Saudi Arabia.ORCID 0000-0003-1789-2239
Hind AlthagafiDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671 Saudi Arabia.ORCID 0009-0003-4662-3895
Atif Abdulwahab A OyouniDepartment of Biology, Faculty of Science, University of Tabuk, Tabuk, Saudi Arabia.ORCID 0000-0001-8762-4999
Abdullah A A AlghamdiDepartment of Biology, Faculty of Science, Al-Baha University, Al-Baha, Saudi Arabia.ORCID 0000-0003-3136-9081
Abdullah M AlmotayriDepartment of Biology, Faculty of Science, Al-Baha University, Al-Baha, Saudi Arabia.
Fawzya AlOmariDepartment of Biology, Faculty of Science, Al-Baha University, Al-Baha, Saudi Arabia.
Deyala M NaguibBotany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, Egypt.ORCID 0000-0001-7164-7838

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

However, the cytotoxic and antioxidant properties of halophyteshave been previously reported, the underlying molecular mechanisms remain poorly understood. In the present study, we not only evaluate the cytotoxic and antioxidant potential of extracts from halophytic species but also, for the first time, elucidate their mechanistic mode of action using an integrated high-content screening and RT-PCR approach to verify apoptosis induction and the modulation of apoptosis-related signaling pathways. Phytochemical screening revealed a diverse array of secondary metabolites, with Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-025-04686-8.

Indexed as

Antioxidant activityApoptosis inductionAvicennia marinaPhytochemicalsSalicornia fruticosa

Identifiers

PMID41808729
PMCPMC12968132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.