Evidence map›Paper›PMID 41808484›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2026

Intratumoural and Peritumoural Radiomics-Based Machine Learning Models for the Postoperative Survival Prediction in Oesophageal Squamous Cell Carcinoma.

Zhi-Qiang Deng, Chen Yang, Zhong-Feng Yan, Yue Li, Hong-Tao Tang, Hou-Dong Zuo, Jun-Jie Zhang, Wen-Long Hu, Yu-Yang Mao, Dai-Yuan Ma and 3 more

Abstract readValidation Study
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zhi-Qiang DengDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.
Chen YangCollege of Medical Imaging, North Sichuan Medical College, Nanchong, 637000, China.
Zhong-Feng YanCollege of Clinical Medicine, North Sichuan Medical College, Nanchong, 637000, China.
Yue LiCollege of Clinical Medicine, North Sichuan Medical College, Nanchong, 637000, China.
Hong-Tao TangDepartment of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.
Hou-Dong ZuoMedical Imaging Key Laboratory of Sichuan Province, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China.
Jun-Jie ZhangCollege of Medical Imaging, North Sichuan Medical College, Nanchong, 637000, China.
Wen-Long HuCollege of Clinical Medicine, North Sichuan Medical College, Nanchong, 637000, China.
Yu-Yang MaoCollege of Clinical Medicine, North Sichuan Medical College, Nanchong, 637000, China.
Dai-Yuan MaDepartment of Oncology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000, China.
Kai-Yuan JiangDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Hao-Ji YanDepartment of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Dong TianDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.ORCID 0000-0001-8510-8309

Funding

Clinical Research Incubation Project of West China Hospital, Sichuan University 2023HXFH042
6 · The paper itself

Abstract

objectivesThis study aimed to develop and validate machine learning (ML) models to predict survival following oesophagectomy in oesophageal squamous cell carcinoma (ESCC) patients using intratumoural and peritumoural radiomic features.

methodsA retrospective analysis was conducted on ESCC patients with preoperative contrast-enhanced computed tomography who underwent oesophagectomy from June 2016 to January 2020. Patients were randomly assigned to training and test sets (8:2 ratio). Radiomic features were independently extracted from intratumoural and peritumoural regions. Cox regression, random survival forests (RSF), and gradient boosting decision tree (GBDT) were used for modelling. The performance of models was evaluated by discrimination and calibration.

resultsThe study included 443 patients, 354 in the training set and 89 in the test set. Peritumoural radiomic features predominated in the final selection, with 14 of 17 selected features originating from peritumoural region. The optimal GBDT model (the integrated area under the curve [iAUC]: 0.854; the integrated Brier score [iBS]: 0.160) using dual-region radiomic and clinical features outperformed other models, with a 1-year time-dependent area under the curve (tAUC) of 0.712 (95% CI, 0.655-0.738) and 3-year tAUC of 0.733 (95% CI, 0.655-0.805). It effectively stratified patients into high- and low-risk groups (P < .001).

conclusionsML models using intratumoural and peritumoural radiomic features showed potential for predicting postoperative survival in ESCC patients, with the optimal GBDT model demonstrating effective risk stratification.

Indexed as

Esophageal NeoplasmsEsophageal Squamous Cell CarcinomaEsophagectomyMachine LearningRadiomicsTomography, X-Ray ComputedAgedBoosting Machine Learning AlgorithmsFemaleHumansMaleMiddle AgedPredictive Learning ModelsPredictive Value of TestsRetrospective StudiesRisk Assessmentmachine learningoesophageal squamous cell carcinomaradiomicssurvival

Identifiers

PMID41808484
PMCPMC12987764

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.