Evidence map›Paper›PMID 41808074›Full record

ArticleBMC geriatrics2026

Sex differences in the associations between illness representations and behavioral intentions to seek early Alzheimer's detection in Chinese older adults.

Hui Lu, Sixuan Chen, Yiping Tang, Wenke He, Shenhang Xia, Yili Wu

Abstract read
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hui Lu *Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Key Laboratory of Alzheimer's Disease of Zhejiang Province, Wenzhou Key Laboratory of Basic and Translational Research for Mental Disorders, School of Mental Health, Institute of Aging, Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Sixuan Chen *Wenzhou Key Laboratory of Basic and Translational Research for Mental Disorders, School of Mental Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Institute of Aging, Key Laboratory of Alzheimer's Disease of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Yiping TangWenzhou Key Laboratory of Basic and Translational Research for Mental Disorders, School of Mental Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Institute of Aging, Key Laboratory of Alzheimer's Disease of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Wenke HeWenzhou Key Laboratory of Basic and Translational Research for Mental Disorders, School of Mental Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Institute of Aging, Key Laboratory of Alzheimer's Disease of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Shenhang XiaWenzhou Key Laboratory of Basic and Translational Research for Mental Disorders, School of Mental Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Institute of Aging, Key Laboratory of Alzheimer's Disease of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Yili WuWenzhou Key Laboratory of Basic and Translational Research for Mental Disorders, School of Mental Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Institute of Aging, Key Laboratory of Alzheimer's Disease of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. wuyili@wmu.edu.cn.

Funding

Department of Science and Technology of Zhejiang Province 2023ZY1018General Scientific Research Project of the Zhejiang Provincial Department of Education Y202353191National Natural Science Foundation of China 82271482Oujiang Laboratory OJQDSP2022013
6 · The paper itself

Abstract

objectivesAlzheimer’s disease (AD) is the most common form of dementia in older adults with no cure. Early detection and intervention are critical for improving patient outcomes. However, behavioral intentions to seek early detection of AD (BI-SEDAD) remain low. Illness representations, referring to individuals’ beliefs about illness, may influence BI-SEDAD. This study aimed to investigate the associations between illness representations and BI-SEDAD among Chinese older adults, and potential sex differences in these associations.

methodsA survey was conducted among 509 Chinese older adults. Participants completed the assessment of BI-SEDAD and illness representations of AD. Moderation analyses were conducted using SPSS PROCESS.

resultsConsequences (β = 0.26), timeline (β = 0.23), illness identity (β = 0.22), illness coherence (β = 0.21), illness concern (β = 0.22), and emotional representations (β = 0.24) were positively associated with BI-SEDAD, whereas treatment control was negatively associated (β = − 0.10). Moreover, sex significantly moderated the associations between BI-SEDAD and consequences (β = − 0.20), treatment control (β = 0.21), illness identity (β = − 0.17), illness coherence (β = − 0.25), and illness concern (β = − 0.26). Specifically, the associations between BI-SEDAD and consequences, illness identity, illness coherence, and illness concern were stronger in males than in females. The association between BI-SEDAD and treatment control was significant only in males.

conclusionsIllness representations are important predictors of BI-SEDAD, with notable sex differences. Tailored interventions that address key beliefs and consider sex differences may promote early detection in older populations.

Indexed as

Alzheimer DiseaseEast Asian PeopleIntentionPatient Acceptance of Health CareSex FactorsAgedAged, 80 and overChinaEarly DiagnosisFemaleHumansMaleAlzheimer’s diseaseBehavioral intentionsHealth-seekingIllness perceptionSex differences

Identifiers

PMID41808074
PMCPMC13085351

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.