Evidence map›Paper›PMID 41807939›Full record

ArticleBMC ophthalmology2026

Evaluation of 7 modern IOL power calculation formulas in two PARTIAL-Range of Field IOL designs and a new constant optimization method.

Meiyi Zhu, Zongsheng Zeng, Ziling Zhang, Guangbin Zhang

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Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

Meiyi Zhu *Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, No.336 Xiahe Road, Xiamen, China.
Zongsheng Zeng *Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, No.336 Xiahe Road, Xiamen, China.
Ziling Zhang *Xiamen Huaxia University, Xiamen, Fujian, China.
Guangbin ZhangXiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, No.336 Xiahe Road, Xiamen, China. 386975604@qq.com.

Funding

Fujian Provincial Natural Science Foundation 2023J011590
6 · The paper itself

Abstract

purposeTo evaluate the performance of seven modern intraocular lens (IOL) power calculation formulas in two different PARTIAL-Range of Field (RoF) extend IOL designs, and a novel IOL constant optimization method.

methods200 eyes implanted with Acrysof IQ Vivity or Tecnis Symfony IOL were included. Postoperative refractive outcomes of the Barrett Universal II (BUII), Cooke K6, EVO 2.0, Hill-RBF 3.0, Hoffer QST, Kane, and Pearl DGS formulas were compared. IOL constant is optimized by using ‘three variable optimization’ (TVO) ( https://ioloptimization.com/calculator ). Formula Performance Index (FPI), root-mean-square absolute prediction error (RMSAE), and SD of prediction errors were selected as the primary endpoints.

resultsIn the Vivity group, the FPI in descending order was Cooke K6 (0.613), Kane (0.496), Hill-RBF 3.0 (0.478), Pearl DGS (0.474), BUII (0.430), EVO 2.0 (0.405), and Hoffer QST (0.341). No significant inter-formula differences were found in RMSAE and SD. In the Symfony group, the FPI in descending order was Cooke K6 (0.495), Pearl DGS (0.473), Hill-RBF 3.0 (0.428), BUII (0.403), Kane (0.385), EVO 2.0 (0.352), and Hoffer QST (0.310). Cooke K6 outperformed Hoffer QST (P = 0.032) and Pearl DGS (P = 0.027) in SD. The optimized A-constants vary among formulas derived from the same IOL model (Vivity: range 118.97 to 119.14; Symfony: range 119.17 to 119.36). All formulas achieved a mean prediction error of less than 0.012 D after constant optimization.

conclusionsModern IOL power calculation formulas exhibit high accuracy for PARTIAL-RoF extend IOLs, with performance varying by IOL model. The TVO proved to be an effective and convenient tool.

Indexed as

BiometryLenses, IntraocularOptics and PhotonicsRefraction, OcularAgedFemaleHumansLens Implantation, IntraocularMiddle AgedPhacoemulsificationProsthesis DesignVisual AcuityIOL constant optimizationIOL power calculation formulaPARTIAL-Range of Field IOL

Identifiers

PMID41807939
PMCPMC12977403

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.