Evidence map›Paper›PMID 41807743›Full record

ArticleJournal of ophthalmic inflammation and infection2026

CMV retinitis: the diagnostic challenges and long-term outcomes. The experience of tertiary eye center in Saudi Arabia.

Abdulrahman AlZaid, Abdulrahman Khan, Hassan Al-Dhibi, Moustafa S Magliyah

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Article in Journal of ophthalmic inflammation and infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Abdulrahman AlZaidVitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia.
Abdulrahman KhanVitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia.
Hassan Al-DhibiVitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia.
Moustafa S MagliyahVitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia. mmagliyah@kkesh.med.sa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the clinical features, complications, and long-term visual outcomes of cytomegalovirus (CMV) retinitis in patients presenting to a tertiary eye center.

methodsA retrospective chart review of patients who were diagnosed with CMV retinitis between 2014 and 2024.

resultsTwelve eyes of 8 patients were included. Five patients (62.5%) were males and 3 (37.5%) were females. All patients were immunocompromised. Four patients (40%) were on immunosuppressive medications after renal transplantations for chronic renal failure (CRF), three patients had human immunodeficiency virus (HIV) infections, and one patient had a congenital immunodeficiency disease. The baseline best-corrected visual acuity (BCVA) was 0.8 ± 0.9 (Snellen = 20/125). Seven eyes (58.3%) had a hemorrhagic type of retinitis, and 5 eyes had granular retinitis (41.7%). Vitritis was found only in 2 eyes (16.7%), vasculitis was found in 3 eyes (25%), and occlusive vasculitis was found in 2 eyes (16.7%), and all of these features were present in patients who were non-HIV infected. The mean BCVA on the last visit was 0.9 ± 1.2 (Snellen = 20/160). Visual threatening complications included macular atrophy, optic disc pallor, rhegmatogenous retinal detachment (RRD), and NVG.

conclusionThe clinical picture of CMV retinitis is better related to the level of immunity than the classification of HIV vs. non-HIV related. Signs of inflammatory response were absent in HIV-infected patients.

Indexed as

CMV retinitisHIVImmunocompromised statusRetinal detachmentValganciclovir

Identifiers

PMID41807743
PMCPMC13087059

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