Trial reportScientific reports2026
GP perspectives on a computer-assisted strategy to support PPI deprescribing: a qualitative study.
Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Refining MediQuit: an iterative, participatory approach to shared decision-making in deprescribing.Implementation science communications · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proton pump inhibitors (PPIs) are widely prescribed in primary care but often continued longer than clinically necessary, exposing patients to avoidable risks. Digital decision-support tools have been proposed to assist clinicians in identifying and managing potentially inappropriate medications. The arriba-PPI tool was developed to facilitate conversations on PPI deprescribing between general practitioners (GPs) and patients, supporting evidence-based and shared decision-making. To explore GPs' experiences with the arriba-PPI tool in clinical practice and understand factors influencing its use and impact on PPI prescribing and discontinuation. A qualitative exploratory study embedded within a multicentre cluster-randomised controlled trial conducted in German general practices. Semi-structured interviews were conducted with 26 GPs from the intervention arm who had used the tool. Interviews were analysed following Braun and Clarke's six-step thematic analysis methodology, applying a combined deductive-inductive approach. Six main themes emerged: perceived usefulness and acceptance of the tool; tool functionality and areas for improvement; patient perspectives and characteristics; doctor-patient interaction and consultation dynamics; PPI prescribing and discontinuation practices; and implementation context and long-term use. GPs valued the tool's structured format and visual aids for enhancing communication, particularly with patients reluctant to stop PPIs. Some described an educational benefit, reporting greater awareness and reflection on their own prescribing behaviour. Barriers to sustained use included technical issues, workflow integration challenges, and the absence of non-pharmacological alternatives. Trust and established doctor-patient relationships were seen as critical for successful deprescribing, often surpassing the tool's direct influence. While the arriba-PPI tool supports deprescribing conversations, its effectiveness depends on seamless integration, technical optimisation, and complementary non-drug strategies. Future digital interventions should follow established frameworks for complex intervention development, adopt a more holistic approach, and combine technological support with broader patient-centred care to achieve sustained deprescribing success in primary care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.