Evidence map›Paper›PMID 41807458›Full record

ArticleNature communications2026

Magnetic-driven multifunctional optoelectronic catheter for in vivo chemical mapping and precisely guided-tumor therapy.

Fuqian Chen, Xiaxu Liu, Yuanxi Zhang, Ying Zheng, Jingbo Yang, Tong Wu, Ke Zhao, Weiyuan Chen, Yuanyuan Li, Xia Gong and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Fuqian ChenGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.
Xiaxu LiuGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.
Yuanxi ZhangGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.ORCID http://orcid.org/0009-0004-6254-0747
Ying ZhengGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.
Jingbo YangGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.
Tong WuGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.
Ke ZhaoGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.
Weiyuan ChenGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.
Yuanyuan LiGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.
Xia GongGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.
Hui WangDepartment of Neurosurgery, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Shuo WuGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China. wush68@sysu.edu.cn.
Xi XieGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China. xiexi27@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0001-7406-8444
Lelun JiangGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China. jianglel@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-5530-3266

Funding

National Natural Science Foundation of China (National Science Foundation of China) T2225010, 52305442, 52305458, 52175446, 52405329, and 32171399Natural Science Foundation of Guangdong Province (Guangdong Natural Science Foundation) 2022B1515020011
6 · The paper itself

Abstract

Precision tumor theranostic in minimally invasive interventions still face challenges such as poor navigational flexibility and limited functional integration. Here, we present a 2.5 mm magnetic-driven multifunctional optoelectronic catheter (MDMOC) fabricated via 3D multi-axis printing for in situ tumor mapping and therapy. The MDMOC integrates magnetic navigation, targeted drug delivery, localized photodynamic therapy, X-ray trackable imaging, and multiplexed biosensing of metabolites and ions. Its magneto-optical-electric-fluid multimodal design enables navigation through complex pathways, simultaneously monitoring biomarkers across the tumor microenvironment and delivering localized therapy. In rabbit and mouse tumor models, the MDMOC distinguished tumor from normal tissue, guided precise therapy, and minimized systemic side effects. In a Bama pig model, it achieved accurate navigation, multiparametric sensing, and targeted contrast agent delivery in complex anatomy. By integrating diagnostic and therapeutic functions with remote magnetic control, the MDMOC provides a versatile platform for real-time, precision-guided tumor diagnosis and therapy.

Indexed as

CathetersNeoplasmsAnimalsCell Line, TumorContrast MediaDrug Delivery SystemsFemaleHumansMagneticsMicePhotochemotherapyRabbitsSwineTumor MicroenvironmentContrast Media

Identifiers

PMID41807458
PMCPMC13103385

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.