ArticleJournal of insect science (Online)2026
Identification of a high-activity and ubiquitous promoter from lepidoptera insect for transgenic applications.
Article in Journal of insect science (Online), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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5 authors.
Funding
Abstract
The domesticated silkworm, Bombyx mori, represents a pivotal lepidopteran model for functional genomics and genetic engineering. Despite its utility, the limited repertoire of characterized endogenous promoters constrains advanced genetic manipulation in this species. Here, we report the discovery and functional validation of BmOvoP, a novel 1,206-bp endogenous promoter derived from the BmOvo locus. Transgenic B. mori expressing enhanced green fluorescent protein (EGFP) under BmOvoP regulation exhibited sustained, pan-tissue fluorescence from embryogenesis to adulthood, defining its utility as a developmentally stable, high-efficiency promoter. Quantitative assays in both BmN cell cultures and transgenic lines confirmed robust, ubiquitous EGFP expression, including robust activity in gonads, a historically challenging target for constitutive promoters. Lepidoptera insects exhibit a remarkable diversity of species, yet research on universal and tissue-specific promoters remains limited. Here, we report that BmOvoP's functionality was conserved in the agriculturally significant lepidopteran pest Ostrinia furnacalis, demonstrating cross-species compatibility. This work establishes BmOvoP as a versatile genetic tool for B. mori and related Lepidoptera, addressing a critical gap in lepidopteran transgenics.
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