Evidence map›Paper›PMID 41807047›Full record

ArticleLife science alliance2026

The CDKL5 kinase undergoes liquid-liquid phase separation driven by a serine-rich C-terminal region.

Stefania Boggio Bozzo, Marco Dell'Oca, Serena Vaglietti, Antonia Gurgone, Vita Cardinale, Gregorio Ragazzini, Andrea Alessandrini, Luca Colnaghi, J Fernando Bazan, Mirella Ghirardi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stefania Boggio BozzoRita Levi-Montalcini Department of Neuroscience, University of Turin, Turin, Italy.ORCID 0009-0003-4521-6569
Marco Dell'OcaRita Levi-Montalcini Department of Neuroscience, University of Turin, Turin, Italy.
Serena VagliettiRita Levi-Montalcini Department of Neuroscience, University of Turin, Turin, Italy.
Antonia GurgoneRita Levi-Montalcini Department of Neuroscience, University of Turin, Turin, Italy.
Vita CardinaleRita Levi-Montalcini Department of Neuroscience, University of Turin, Turin, Italy.
Gregorio RagazziniDepartment of Physics, Informatics and Mathematics, University of Modena, Modena, Italy.
Andrea AlessandriniDepartment of Physics, Informatics and Mathematics, University of Modena, Modena, Italy.
Luca ColnaghiDivision of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
J Fernando Bazanℏ Bioconsulting LLC, Stillwater, MN, USA.
Mirella GhirardiRita Levi-Montalcini Department of Neuroscience, University of Turin, Turin, Italy.
Maurizio GiustettoRita Levi-Montalcini Department of Neuroscience, University of Turin, Turin, Italy maurizio.giustetto@unito.it.ORCID 0000-0003-1323-4060
Ferdinando FiumaraRita Levi-Montalcini Department of Neuroscience, University of Turin, Turin, Italy ferdinando.fiumara@unito.it.ORCID 0000-0003-0715-7863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

Protein Serine-Threonine KinasesSerineAnimalsEpileptic SyndromesHumansPhase SeparationProtein DomainsSpasms, InfantileCDKL5 protein, humanProtein Serine-Threonine KinasesSerine

Identifiers

PMID41807047
PMCPMC12976563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.