Evidence map›Paper›PMID 41807045›Full record

ArticleInternational journal of spine surgery2026

Can the Stand-Alone Cervical Interfacet Fusion Achieve Spinal Stability? A Comprehensive Finite Element Analysis.

Luca Ciriello, Margherita Rotondi, Giuseppe J Sciarrone, Tomaso Villa

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Article in International journal of spine surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luca Ciriello *Department of Chemistry, Materials and Chemical Engineering "Giulio Natta" - LaBS, Politecnico di Milano, Milan, Italy.
Margherita Rotondi *Department of Chemistry, Materials and Chemical Engineering "Giulio Natta" - LaBS, Politecnico di Milano, Milan, Italy.
Giuseppe J SciarroneMinimally Invasive Spine Surgery, Humanitas-San Pio X Hospital, Milan, Italy.
Tomaso VillaDepartment of Chemistry, Materials and Chemical Engineering "Giulio Natta" - LaBS, Politecnico di Milano, Milan, Italy tomaso.villa@polimi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDegenerative pathologies of the cervical spine often involve facet and disc degeneration, leading to biomechanical instability of the cervical spine. A promising surgical solution is a cervical interfacet fusion system (CIFS), typically combined with an anterior disc cage to promote bone fusion and restore stability. However, the necessity of the anterior disc cage remains controversial because it increases surgical time, cost, and risk. The aim of this study was to evaluate the biomechanical performance of CIFS alone compared with its combination with an anterior disc cage using a C2-C7 finite element model.

methodsThe model was validated against literature data in terms of range of motion (RoM) and used to simulate 3 surgical scenarios: (i) anterior disc cage alone, (ii) CIFS alone, and (iii) CIFS combined with an anterior disc cage. Simulations were performed with C4-C5, C5-C6, and C4-C6 treated levels under flexion, extension, axial rotation, and lateral bending.

resultsModels (i) and (iii) eliminated motion at the treated levels but induced hypermobility and increased intradiscal pressure (IDP) at adjacent levels. Conversely, model (ii) preserved residual motion at the treated levels, providing mobility with RoM values within the average range of a healthy population and reducing intradiscal pressure at both the treated and adjacent levels, potentially protecting adjacent discs. However, model (ii) has a higher risk of pseudarthrosis due to the residual motion. CLINICAL RELEVANCE: This study highlights how a CIFS in cervical spine surgery is a cost-effective alternative that preserves mobility but requires careful patient selection to minimize risks such as pseudarthrosis and adjacent segment degeneration while emphasizing the need for postoperative muscle rehabilitation.

conclusionsThese results suggest that CIFS alone may provide a treatment that is both cost-effective and capable of preserving mobility with RoM values within the average range of a healthy population, especially with appropriate patient selection and muscle rehabilitation. LEVEL OF EVIDENCE: 5:

Indexed as

anterior disc cagecervical columncervical instabilitycervical interfacet fusion systemscervical radiculopathyfinite element model

Identifiers

PMID41807045
PMCPMC13153919

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.