Evidence map›Paper›PMID 41806344›Full record

ArticleBulletin of experimental biology and medicine2025

Effect of Anti-Glutamate Antibodies on the Content of IL-4 and IL-10 in Brain Structures in Aged Mice with Induced Memory Impairment.

T V Davydova, L A Vetrile, I A Zakharova

Abstract read
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Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

T V DavydovaInstitute of General Pathology and Pathophysiology, Moscow, Russia. dav-ta@yandex.ru.
L A VetrileInstitute of General Pathology and Pathophysiology, Moscow, Russia.
I A ZakharovaInstitute of General Pathology and Pathophysiology, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intranasal administration of the neurotoxic fragment of β-amyloid protein Aβ25-35 for 14 days to aged C57Bl/6 mice induces impairment of passive avoidance conditioning and reduces the content of IL-10 in the prefrontal cortex and hippocampus without changing the content of IL-4 in these brain structures. Co-administration of Aβ25-35 with anti-glutamate antibodies reversed spatial memory impairment, restores the levels of IL-10, and reduces the content of IL-4 in the prefrontal cortex and hippocampus of aged C57Bl/6 mice.

Indexed as

AntibodiesGlutamic AcidInterleukin-10Interleukin-4Memory DisordersAgingAmyloid beta-PeptidesAnimalsAvoidance LearningHippocampusMaleMiceMice, Inbred C57BLPeptide FragmentsPrefrontal CortexAmyloid beta-Peptidesamyloid beta-protein (25-35)AntibodiesGlutamic AcidIL10 protein, mouseIl4 protein, mouseInterleukin-10Interleukin-4Peptide Fragmentsantibodiesglutamateinterleukin-10interleukin-4memory

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.