Evidence map›Paper›PMID 41806339›Full record

ArticleChemistryOpen2026

A Hybrid Nanosystem for Prostate Cancer Therapy: Codelivery of Enzalutamide and Curcumin via Selenium-Embedded Mesoporous Silica and Chitosan Nanoparticles.

Zahra Tavakoli, Khosro Khajeh, Bijan Ranjbar

Abstract read
In one paragraph

Article in ChemistryOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zahra TavakoliDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.ORCID 0009-0003-9170-028X
Khosro KhajehDepartment of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Bijan RanjbarDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.ORCID 0000-0001-7373-5030

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the second most common cancer globally, causing ≈396,792 deaths in 2022. Early diagnosis and advanced drug delivery are vital to prevent its progression. This research leverages the anticancer properties of selenium nanoparticles and enzalutamide, a leading prostate cancer drug, by coencapsulating them within mesoporous silica nanoparticles (MSNPs). MSNPs offer advantages for drug delivery, including high surface accessibility and a tunable porous structure. The results indicated that MSNPs synthesized via solvent extraction, yielding a specific surface area of 1017.4 m

Indexed as

Antineoplastic AgentsBenzamidesChitosanCurcuminNanoparticlesNitrilesPhenylthiohydantoinProstatic NeoplasmsSeleniumSilicon DioxideApoptosisCell Line, TumorCell ProliferationCell SurvivalDrug CarriersDrug LiberationAntineoplastic AgentsBenzamidesChitosanCurcuminDrug CarriersenzalutamideNitrilesPhenylthiohydantoinSeleniumSilicon Dioxidecurcuminenzalutamidemesoporous silicaprostate cancerselenium

Identifiers

PMID41806339
PMCPMC12974330

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.