Evidence map›Paper›PMID 41806299›Full record

ArticleThe Journal of physiology2026

Robust activity-dependent mitochondrial calcium dynamics at the AIS is dispensable for action potential generation.

Koen Kole, Maarten H P Kole

Abstract read
In one paragraph

Article in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Koen KoleDepartment of Axonal Signaling, Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Science, Amsterdam, The Netherlands.ORCID 0000-0002-5750-9081
Maarten H P KoleDepartment of Axonal Signaling, Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Science, Amsterdam, The Netherlands.ORCID 0000-0002-3883-5682

Funding

Exacte en Natuurwetenschappen 865.17.003Netherlands Organisation for Health Research and Development 0 451 001 201 0066
6 · The paper itself

Abstract

Mitochondria are diverse and multifaceted intracellular organelles regulating oxidative energy supply, lipid metabolism and calcium (Ca

Indexed as

Action PotentialsAxon Initial SegmentCalciumMitochondriaPyramidal CellsAnimalsCalcium ChannelsCalcium SignalingMiceCalciumCalcium Channelsaction potentialaxon initial segmentcalcium buffermitochondriapyramidal neuron

Identifiers

PMID41806299
PMCPMC13039255

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.