ArticleEuropean journal of ageing2026
Contribution of accumulative affective problems across the life course towards the association of childhood socioeconomic position with later-life cognitive ageing.
Article in European journal of ageing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Cognitive ageing among older Latin American immigrants: current evidence and limitations.Frontiers in aging neuroscience · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Socioeconomic inequalities may act on affective and cognitive health from early life through later life. This study tested to what extent the association of childhood socioeconomic position (SEP) with later-life cognitive ageing is explained by life course accumulative affective problems. We used data from the MRC National Survey of Health and Development (n = 1,593; 52.6% women). Cognitive ageing was assessed through a battery of neuropsychological tests. Later-life cognitive function was assessed at age 69, and cognitive decline was measured across ages 53, 60-64, and 69. Childhood SEP was derived from overcrowding, essential household amenities, housing condition, and paternal occupation. Affective problems measured at ages 13-64 were categorized into case-level thresholds (never/once/twice or more). Multiple linear and logistic regression analyses and causal mediation models tested associations between childhood SEP, affective problems, and later-life cognitive ageing. Low childhood SEP was associated with lower scores on later-life (age 69) verbal memory (B = - 1.87[- 2.48; - 1.25]), letter search speed (B = - 9.98[- 17.57; - 2.40]), letter search accuracy (B = - 0.90[- 1.44; - 0.37]), cognitive state (B = - 2.14[- 2.82; - 1.46]), and accelerated decline (between ages 53-69) in letter search accuracy (B = 0.82[0.17; 1.46]), but slower decline in verbal memory (B = - 0.27[- 0.51; - 0.00]) compared to high childhood SEP. Low childhood SEP was associated with life course affective problems once (OR = 1.37[1.09; 1.73]) and twice or more (OR = 1.32[1.01; 1.71]). The association between childhood SEP and later-life letter search accuracy was partly explained (6.3%) by incidental affective problems. In conclusion, although improving affective health across the life course may enhance later-life cognitive ageing, it could only marginally explain the association between childhood SEP and later-life cognitive ageing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.