Trial reportWorld journal of urology2026
Optimal duration between drainage for obstructing renal or ureteral stones associated with infection and ureteroscopic lithotripsy: a randomized controlled trial.
Trial report in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06101563 (Optimal Duration Between Drainage for Obstructing Renal or Ureteral Stones Associated With Infection and Ureteroscopic Lithotripsy), which is not on this map. Not yet cited in PubMed.
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The trial behind it
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Optimal Duration Between Drainage for Obstructing Renal or Ureteral Stones Associated With Infection and Ureteroscopic Lithotripsy: A Randomized Controlled Trial.
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study was done to determine the optimal interval between drainage of obstructed infected kidney and ureteroscopic lithotripsy. PATIENTS AND
methodsThis randomized controlled trial was conducted between May 2023 and July 2024. Inclusion criteria were adult patients with obstructed infected kidneys by renal or ureteric stones. After drainage of the kidney, they were randomized into early and delayed groups. In the early group, ureteroscopy was done after 7 days while in the delayed group, ureteroscopy was done after 14–21 days of drainage. The primary outcome was the difference in incidence of postoperative infectious complications. Infectious complications were defined as having one of the criteria of systemic inflammatory response syndrome (SIRS) with infected urine culture. Secondary outcomes were unplanned visits during the waiting period, hospital stay and stone-free rates (SFR).
resultsThe study included 96 patients (44 in early group and 52 in delayed group). Post-ureteroscopy infectious complications were significantly more in the early group (56.8% versus 30.8%, P = 0.01). The rate of unplanned hospital visits during waiting period was higher in the delayed group (36.5% versus 11.4% in the early group, P = 0.005). Hospital stays after ureteroscopy and SFR were comparable between both groups (P = 0.227 and P = 0.464).
conclusionsThe preferred timing for ureteroscopy after drainage of obstructed infected kidneys with urolithiasis may be between 14 to 21 days because early intervention was associated with a higher incidence of infectious complications.
trial registrationThe protocol for the trial was registered in ClinicalTrials.gov (NCT06101563) on October 20, 2023.
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