Evidence map›Paper›PMID 41805896›Full record

ArticleThe ultrasound journal2026

Feasibility of measuring left ventricular outflow tract velocity time integral as a predictor for stroke volume in pregnant women in labor.

Mohamed Eissa, George Dumitrascu, Elizabeth Miller, Jennifer Racine, Victoria Postnikova, Wesley Rajaleelan, Wesley Edwards, Hesham Talab, Daniel McIsaac

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Article in The ultrasound journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Mohamed EissaDepartment of Anesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital, Ottawa, ON, Canada; Ottawa Hospital Research Institute, Ottawa, ON, Canada; Ain Shams University, Cairo, Egypt.ORCID 0000-0003-1014-6866
George DumitrascuDepartment of Anesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital, Ottawa, ON, Canada.
Elizabeth MillerDepartment of Anesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital, Ottawa, ON, Canada.
Jennifer RacineDepartment of Anesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital, Ottawa, ON, Canada.
Victoria PostnikovaDepartment of Anesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital, Ottawa, ON, Canada.
Wesley RajaleelanDepartment of Anesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital, Ottawa, ON, Canada.
Wesley EdwardsDepartment of Anesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital, Ottawa, ON, Canada.
Hesham TalabDepartment of Anesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital, Ottawa, ON, Canada; Ain Shams University, Cairo, Egypt.
Daniel McIsaacDepartment of Anesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital, Ottawa, ON, Canada; Ottawa Hospital Research Institute, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPregnancy is a time of significant hemodynamic changes. Maintaining adequate cardiac output (CO) and uteroplacental perfusion is a priority in parturients, for favorable maternal-fetal outcomes. Blood pressure is commonly used as a surrogate for CO, although it may poorly correlate with stroke volume (SV) and CO in some cases. An alternative approach is SV estimation using transthoracic echocardiography (TTE) based on the velocity-time integral (VTI) of the left ventricular outflow tract (LVOT). Although VTI has been validated as a tool to estimate SV and CO in acute care contexts, its feasibility and utility in obstetric anesthesia remain unexplored. Therefore, the objective of this study is to evaluate the feasibility and reproducibility of LVOT VTI measurements in parturients during labor.

methodsFollowing research ethics board approval, 55 full term pregnant female patients with a singleton pregnancy were recruited. TTE was used to calculate the LVOT VTI for each patient by the same anesthesiologist twice. Feasibility of obtaining the LVOT VTI was evaluated using time for image acquisition and the 3-Point Likert Scale for Imaging Quality. Intraclass correlation coefficients (ICC) were used to estimate intra-rater reliability.

resultsLVOT VTI was obtained for all participants on both attempts. Mean time needed to obtain measurements was 63.7 seconds (95%CI 56.5 to 70.8) on the 1st attempt and 44.2 seconds (95%CI 38.7 to 49.8) on the 2nd attempt. Eighty-one (73.6%) images were rated as optimal, 29 (26.3%) were rated as suboptimal. Intra-rater reliability was excellent (ICC was 0.94 (95%CI 0.92 to 0.95).

conclusionIn singleton parturients, LVOT VTI measurements can be routinely obtained in a timely fashion with excellent intra-rater reliability during labor. These results support the feasibility of LVOT VTI to estimate and trend SV.

Identifiers

PMID41805896
PMCPMC13320601

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.