Evidence map›Paper›PMID 41805639›Full record

ReviewHuman vaccines & immunotherapeutics2026

Safety, immunogenicity, and effectiveness of the MAV/06 varicella vaccine: A comprehensive review of a new strain vaccine.

Younchul Shin, Hyunji Ryu, Gwanglok Kim, Shinha Yang, Jaewoo Lee, BongKyoo Choi

Abstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Younchul ShinDevelopment of Research and Development, GC Biopharma Corp., Yongin, Republic of Korea.
Hyunji RyuDevelopment of Research and Development, GC Biopharma Corp., Yongin, Republic of Korea.
Gwanglok KimDevelopment of Research and Development, GC Biopharma Corp., Yongin, Republic of Korea.
Shinha YangDevelopment of Research and Development, GC Biopharma Corp., Yongin, Republic of Korea.
Jaewoo LeeDevelopment of Research and Development, GC Biopharma Corp., Yongin, Republic of Korea.
BongKyoo ChoiDevelopment of Research and Development, GC Biopharma Corp., Yongin, Republic of Korea.ORCID 0000-0002-7087-9378

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most of licensed varicella vaccines are based on the Oka strain, while MAV/06 strain vaccines were exclusively developed by GC Biopharma Corp. in South Korea. This paper aims to summarize and present more than 30 y of accumulated evidence from about 40 unpublished and published studies on safety, immunogenicity, and effectiveness of MAV/06 vaccines. The safety of MAV/06 vaccines has been confirmed through various clinical trials and post-marketing studies. Outstanding humoral and cell-mediated immunogenicity of the MAV/06 vaccines has been demonstrated in diverse clinical trials and real-world studies. For example, a seroconversion rate of the MAV/06 vaccine (BARYCELA inj.) was close to 100%. Moreover, several after-approval epidemiological studies in Korean and Filipino children have supported the effectiveness of MAV/06 vaccines, although it remains to be further confirmed in future studies. In terms of safety, immunogenicity, and effectiveness, MAV/06 strain varicella vaccines are comparable to Oka strain vaccines.

Indexed as

ChickenpoxChickenpox VaccineImmunogenicity, VaccineVaccine EfficacyAntibodies, ViralClinical Trials as TopicHerpesvirus 3, HumanHumansRepublic of KoreaAntibodies, ViralChickenpox Vaccinecost-effectiveeffectivenessimmunogenicityMAV/06 strainsafetyVaricella vaccines

Identifiers

PMID41805639
PMCPMC12977269

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.