Evidence map›Paper›PMID 41805565›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Crystal structure of

Ranjuna Weerasekera, Alexis Moreau, Xin Huang, Anna Potapova, Carmen Schwechheimer, Rajan Kandel, Yun Huynh, Owen Cannizzo, Ryan Gordon, Emma Gerace and 7 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ranjuna WeerasekeraDepartment of Molecular Biology and Biochemistry, Molecular Biophysics Program, Wesleyan University, Middletown, CT 06459.ORCID 0000-0002-4740-9474
Alexis MoreauDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520.ORCID 0000-0002-0559-6179
Xin HuangDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520.ORCID 0000-0003-1745-8598
Anna PotapovaDepartment of Microbiology and Environmental Toxicology, University of California, Santa Cruz, CA 95064.ORCID 0000-0002-6855-8954
Carmen SchwechheimerDepartment of Microbiology and Environmental Toxicology, University of California, Santa Cruz, CA 95064.
Rajan KandelComplex Carbohydrate Research Center, University of Georgia, Athens, GA 30602.ORCID 0009-0006-9060-9777
Yun HuynhDepartment of Molecular Biology and Biochemistry, Molecular Biophysics Program, Wesleyan University, Middletown, CT 06459.
Owen CannizzoDepartment of Molecular Biology and Biochemistry, Molecular Biophysics Program, Wesleyan University, Middletown, CT 06459.
Ryan GordonDepartment of Molecular Biology and Biochemistry, Molecular Biophysics Program, Wesleyan University, Middletown, CT 06459.
Emma GeraceDepartment of Molecular Biology and Biochemistry, Molecular Biophysics Program, Wesleyan University, Middletown, CT 06459.
Alexander J HinbestDepartment of Molecular Biology and Biochemistry, Molecular Biophysics Program, Wesleyan University, Middletown, CT 06459.
Yiyan YangNational Library of Medicine, National Institutes of Health, Bethesda, MD 20894.
Xiaofang JiangNational Library of Medicine, National Institutes of Health, Bethesda, MD 20894.
Robert J WoodsComplex Carbohydrate Research Center, University of Georgia, Athens, GA 30602.ORCID 0000-0002-2400-6293
Jing YanDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520.ORCID 0000-0003-2773-0348
Fitnat H YildizDepartment of Microbiology and Environmental Toxicology, University of California, Santa Cruz, CA 95064.ORCID 0000-0002-6384-7167
Rich OlsonDepartment of Molecular Biology and Biochemistry, Molecular Biophysics Program, Wesleyan University, Middletown, CT 06459.ORCID 0000-0002-5432-206X

Funding

X-ray Scattering Technology CoreP30GM133893 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI Sean McSweeney · 2019 to 2026
$38.6M
Vibrio cholerae biofilms: structure, function, regulation and role in infectionR01AI114261 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2014 to 2024
$5.0M
Tracking single-cell gene expression heterogeneity and its consequences in bacterial biofilmsDP2GM146253 · NIGMS · YALE UNIVERSITY · PI YAN, JING · 2021 to 2024
$2.5M
Structural and functional studies of glycosyl hydrolases governing Vibrio biofilm dispersalR15GM152959 · NIGMS · WESLEYAN UNIVERSITY · PI OLSON, RICHARD A · 2023 to 2023
$471k
Alfred P. Sloan Foundation (APSF) FG-2023-20857HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI114261HHS | NIH | National Institute of General Medical Sciences (NIGMS) 1DP2GM146253HHS | NIH | National Institute of General Medical Sciences (NIGMS) R15GM152959NIAID NIH HHS R01 AI114261NIGMS NIH HHS DP2 GM146253NIGMS NIH HHS P30 GM133893NIGMS NIH HHS R15 GM152959NSF | MPS | Division of Materials Research (DMR) 2205006
6 · The paper itself

Abstract

Exopolysaccharides are carbohydrate polymers secreted by bacteria to perform various roles including adhesion to surfaces, protection from environmental stressors, and as key components in the production of biofilms. The human pathogen

Indexed as

Bacterial ProteinsPolysaccharide-LyasesPolysaccharides, BacterialVibrio choleraeBiofilmsCrystallography, X-RayMolecular Dynamics SimulationProtein BindingSubstrate SpecificityBacterial ProteinsPolysaccharide-LyasesPolysaccharides, BacterialbiofilmcholeraexopolysaccharidelyaseX-ray crystallography

Identifiers

PMID41805565
PMCPMC12993940

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.