Evidence map›Paper›PMID 41805380›Full record

SynthesisLupus2026

Psychosis in patients with systematic lupus erythematosus: A systematic literature review and meta-analysis.

Konstantinos Parperis, Panagiotis Zis, Marina Evangelou, Avgoustina Kyriakou, Eleni Koliou, Heraklis Pantelidakis, Andreas Chatzittofis

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Lupus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Konstantinos ParperisDivision of Rheumatology, Department of Medicine, University of Cyprus Medical School, Nicosia, Cyprus.ORCID 0000-0001-6009-0130
Panagiotis ZisDivision of Neurology, Department of Medicine, University of Cyprus Medical School, Nicosia, Cyprus.
Marina EvangelouDepartment of Medicine, University of Cyprus Medical School, Nicosia, Cyprus.ORCID 0000-0003-3394-2988
Avgoustina KyriakouDepartment of Medicine, University of Cyprus Medical School, Nicosia, Cyprus.
Eleni KoliouDepartment of Medicine, University of Cyprus Medical School, Nicosia, Cyprus.
Heraklis PantelidakisDepartment of Neurology, Nicosia General Hospital, Nicosia, Cyprus.
Andreas ChatzittofisDepartment of Psychiatry, University of Cyprus Medical School, Nicosia, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivesPsychosis is a rare but severe neuropsychiatric manifestation of systemic lupus erythematosus (SLE). Its prevalence, clinical predictors, and immunopathogenesis remain incompletely understood. This study aimed to estimate the prevalence of psychosis in adult SLE patients and identify associated clinical and immunological risk factors.MethodsThis systematic review and meta-analysis was conducted following PRISMA guidelines. A comprehensive search of PubMed, Embase, and the Cochrane Library was conducted to identify all relevant studies with ≥10 adults through November 2024. Case-series, case reports, narrative reviews and conference abstracts were excluded. Quality assessment employed the Cochrane Risk of Bias Tool for randomized controlled trials and the Newcastle-Ottawa Scale for observational studies. Statistical analysis was performed using the random-effects model, with heterogeneity assessed via I

Indexed as

Lupus Erythematosus, SystemicPsychotic DisordersAntibodies, AntiphospholipidHumansLupus Vasculitis, Central Nervous SystemPrevalenceRisk FactorsAntibodies, Antiphospholipidanti-ribosomal Pautoantibodiesmeta-analysisneuropsychiatric lupusprevalencepsychosisSystemic lupus erythematosus

Identifiers

PMID41805380
PMCPMC13047237

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.