Evidence map›Paper›PMID 41805357›Full record

ArticleInfection and immunity2026

The

Brittany L Shapiro, Prashant Jaiswal, Lisa J Funkhouser-Jones, Sourav Roy, Taylor J Van Gundy, Jeremy M Bono, Meghan C Lybecker, Brandon L Garcia, Jenny A Hyde, Jon T Skare

Abstract read
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Brittany L ShapiroDepartment of Microbial Pathogenesis and Immunology, Texas A&M University, Bryan, Texas, USA.ORCID 0009-0008-0306-2481
Prashant JaiswalDepartment of Microbial Pathogenesis and Immunology, Texas A&M University, Bryan, Texas, USA.
Lisa J Funkhouser-JonesDepartment of Microbial Pathogenesis and Immunology, Texas A&M University, Bryan, Texas, USA.
Sourav RoyDepartment of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, Kansas, USA.
Taylor J Van GundyBacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Fort Collins, Colorado, USA.
Jeremy M BonoDepartment of Biology, University of Colorado at Colorado Springs, Colorado Springs, Colorado, USA.
Meghan C LybeckerBacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Fort Collins, Colorado, USA.
Brandon L GarciaDepartment of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, Kansas, USA.ORCID 0000-0002-6724-8700
Jenny A HydeDepartment of Microbial Pathogenesis and Immunology, Texas A&M University, Bryan, Texas, USA.
Jon T SkareDepartment of Microbial Pathogenesis and Immunology, Texas A&M University, Bryan, Texas, USA.ORCID 0000-0001-8378-7862

Funding

Regulatory Pathways in Borrelial PathogenesisR01AI170940 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HYDE, JENNY A., SKARE, JON T · 2022 to 2025
$2.7M
The role of small non-coding RNA in borrelial pathogenesisR21AI123672 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HYDE, JENNY A., LYBECKER, MEGHAN · 2016 to 2017
$417k
NIAID NIH HHS R01 AI170940NIAID NIH HHS R21 AI123672
6 · The paper itself

Abstract

Post-transcriptional regulation is an adaptive response used by living systems to alter protein levels independently of transcription initiation. In bacteria, one mechanism of post-transcriptional regulation involves the binding of small, non-coding RNAs (sRNAs) to target mRNAs to regulate their translation into protein. This regulation generally includes an RNA-binding protein that facilitates the sRNA::mRNA interaction. In the etiological agent of Lyme disease,

Indexed as

Bacterial ProteinsBorrelia burgdorferiGene Expression Regulation, BacterialLyme DiseaseRNA, BacterialRNA, Small UntranslatedAnimalsMiceRNA-Binding ProteinsSigma FactorVirulenceBacterial ProteinsRNA, BacterialRNA-Binding ProteinsRNA, Small UntranslatedSigma Factorsigma factor KatF protein, BacteriaBorreliella burgdorferigene regulationLyme diseasepost-transcriptional regulationsRNA

Identifiers

PMID41805357
PMCPMC13081726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.