Evidence map›Paper›PMID 41805262›Full record

ArticleThe Lancet. Microbe2025

New Delhi metallo-β-lactamase-producing Acinetobacter baumannii in the USA from October, 2013, to March, 2022: a retrospective molecular epidemiological analysis.

Magdalena Medrzycki, Richard A Stanton, Danielle A Rankin, Sam Horwich-Scholefield, Arif Mahmud, Tyler Maruca, Sarah Brister, Lian Hsiao, Elisabeth Vaeth, Michelle Therrien and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Lancet. Microbe, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Magdalena MedrzyckiUS Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: lnu6@cdc.gov.
Richard A StantonUS Centers for Disease Control and Prevention, Atlanta, GA, USA.
Danielle A RankinUS Centers for Disease Control and Prevention, Atlanta, GA, USA.
Sam Horwich-ScholefieldCalifornia Department of Public Health Immunization Branch, Sacramento, CA, USA.
Arif MahmudTexas Department of Health, Austin, TX, USA.
Tyler MarucaMaryland Department of Health, Baltimore, MD, USA.
Sarah BristerIllinois Department of Public Health West Chicago Regional Office, Chicago, IL, USA.
Lian HsiaoCalifornia Department of Public Health Immunization Branch, Sacramento, CA, USA.
Elisabeth VaethMaryland Department of Health, Baltimore, MD, USA.
Michelle TherrienTennessee Department of Health, Nashville, TN, USA.
Erin L YoungUtah Department of Health and Human Services, Salt Lake City, UT, USA.
Kelly F OakesonUtah Department of Health and Human Services, Salt Lake City, UT, USA.
Farhana HaqueMaryland Department of Health Laboratories Administration, Baltimore, MA, USA.
Lindsay NeffUtah Department of Public Safety, Salt Lake City, UT, USA.
Alison Laufer HalpinUS Centers for Disease Control and Prevention, Atlanta, GA, USA.
Sarah SabourUS Centers for Disease Control and Prevention, Atlanta, GA, USA.
Jennifer Y HuangUS Centers for Disease Control and Prevention, Atlanta, GA, USA.
Stephen P LaVoieUS Centers for Disease Control and Prevention, Atlanta, GA, USA.
Maroya Spalding WaltersUS Centers for Disease Control and Prevention, Atlanta, GA, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundMost US carbapenem-resistant Acinetobacter baumannii (CRAB) isolates harbour carbapenem-hydrolysing class D β-lactamases. Other carbapenemases, such as New Delhi metallo-β-lactamase (NDM), are uncommon but emerging. We describe the epidemiology of NDM-producing CRAB reported to the US Centers for Disease Control and Prevention (CDC).

methodsWe defined cases as A baumannii with bla

findingsWe identified 327 NDM-CRAB cases from 264 patients in 21 US states. Among patients with available epidemiological information, 192 (90%) of 214 had epidemiological linkage to at least one additional case and 13 (7%) of 193 were hospitalised outside the USA 12 months or less before index specimen collection. Five regionally distinct sequence type clusters were identified among the 264 case patients; three (sequence type

interpretationWe identified regionally distinct NDM-CRAB strains, suggesting localised transmission in the USA. Some NDM-CRAB strains in the USA are closely related to strains identified outside the USA, suggesting that spread followed importation.

fundingNone.

Indexed as

Acinetobacter baumanniiAcinetobacter Infectionsbeta-LactamasesAgedAnti-Bacterial AgentsCarbapenemsFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedMolecular EpidemiologyMultilocus Sequence TypingRetrospective StudiesUnited StatesAnti-Bacterial Agentsbeta-lactamase NDM-1beta-LactamasesCarbapenems

Identifiers

PMID41805262
PMCPMC13267698

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.