Evidence map›Paper›PMID 41805229›Full record

ArticleCritical care medicine2026

Days Alive and at Home After Critical Illness Hospitalization Among Older Adults and Its Association With Delivery of In-Hospital Rehabilitation.

Stephanie Kim, Terrence E Murphy, John R O'Leary, Linda Leo-Summers, Jason R Falvey, Thomas M Gill, Harlan M Krumholz, Lauren E Ferrante, Snigdha Jain

Abstract read
In one paragraph

Article in Critical care medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stephanie KimInternal Medicine, Yale New Haven Hospital, New Haven, CT.
Terrence E MurphyDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, PA.
John R O'LearyProgram on Aging, Yale School of Medicine, New Haven, CT.
Linda Leo-SummersProgram on Aging, Yale School of Medicine, New Haven, CT.
Jason R FalveyPhysical Therapy and Rehabilitation Science, University of Maryland School of Medicine, Baltimore, MD.
Thomas M GillProgram on Aging, Yale School of Medicine, New Haven, CT.
Harlan M KrumholzDepartment of Internal Medicine, Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, CT.
Lauren E FerranteDepartment of Internal Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine, Yale School of Medicine, New Haven, CT.
Snigdha JainDepartment of Internal Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine, Yale School of Medicine, New Haven, CT.ORCID 0000-0003-1712-976

Funding

Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Lauren Ferrante · 2002 to 2026
$37.9M
Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Yale Training Program in Geriatric Clinical Epidemiology and Aging-Related ResearchT32AG019134 · NIA · YALE UNIVERSITY · PI Terri R. Fried · 2001 to 2026
$7.5M
VULNERABILITY, INTERVENING EVENTS &DISABILITY IN AGINGR01AG017560 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2000 to 2025
$7.0M
The PREDICT Study (PRE-ICU Determinants of Post-ICU FunCTional Outcomes among Older Adults)K76AG057023 · NIA · YALE UNIVERSITY · PI FERRANTE, LAUREN · 2017 to 2022
$1.3M
Socioeconomic Disadvantage and Disability Following Critical Illness Among Older Persons: The Role of RehabilitationR03AG078942 · NIA · YALE UNIVERSITY · PI JAIN, SNIGDHA · 2022 to 2023
$335k
NCATS NIH HHS UL1 TR002014NIA NIH HHS K76 AG057023NIA NIH HHS P30 AG021342NIA NIH HHS R01 AG017560NIA NIH HHS R03 AG078942NIA NIH HHS T32 AG019134
6 · The paper itself

Abstract

objectivesOlder adults hospitalized to the ICU are at risk for functional decline. In-hospital rehabilitation can mitigate functional decline; however, its association with long-term outcomes is unknown. Our objective was to describe days alive and at home (DAAH) in the 100 days (DAAH 100 ) after ICU hospitalization among older adults and evaluate whether in-hospital rehabilitation is associated with improved DAAH 100 .

designRetrospective cohort study.

settingNational Health and Aging Trends Study linked with Medicare claims (2011-2019). PATIENTS: Community-dwelling Medicare beneficiaries 65 years old or older who survived ICU hospitalization.

interventionsNone. MEASUREMENTS AND MAIN

resultsThe outcome DAAH 100 was calculated by subtracting all post-discharge days in any of emergency department, observation unit, inpatient medical, psychiatric, rehabilitation unit, skilled nursing or hospice facility, and post-death from 100. The exposure was units of in-hospital rehabilitation, that is, physical and/or occupational therapy. We constructed a proportional odds logistic regression model of DAAH 100 (ordinal) adjusted for demographics, pre-hospitalization frailty and functional status, and hospitalization characteristics. We identified 884 ICU hospitalizations (weighted n = 5,330,486) of older adults discharged alive (age, median [interquartile range (IQR)]: 81 yr [75-86]; 50.5% female). Median DAAH 100 was 95 (IQR: 58.4-100) with median of 4 units (~1 hr) of in-hospital rehabilitation delivered over 6 days. After adjustment, each hour of in-hospital rehabilitation was associated with 8% higher odds of experiencing any of the three highest levels of DAAH 100 after discharge (adjusted odds ratio [95% CI], 1.08 [1.04-1.08]).

conclusionsIn this nationally representative study of older ICU survivors, the average patient spent 95 of the first 100 post-discharge DAAH; delivery of greater amounts of in-hospital rehabilitation was associated with increased DAAH 100 after discharge. These findings highlight the substantial heterogeneity in time spent at home by older ICU survivors and the potential for in-hospital rehabilitation to improve this important patient-centered outcome.

Indexed as

Critical IllnessHospitalizationAgedAged, 80 and overAging in PlaceFemaleHumansIntensive Care UnitsMaleMedicareRetrospective StudiesUnited Statesdays alive and at homeintensive care unit survivorshippost-intensive care syndromerehabilitation

Identifiers

PMID41805229
PMCPMC13091666

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.