Evidence map›Paper›PMID 41804610›Full record

Observational studyNursing open2026

Spirituality and Happiness in Haemodialysis Patients: The Mediating Roles of Life Attitude and Posttraumatic Growth.

Hsiang-Chun Lee, Yi-Chien Chiang, Kun-Hung Tsai, Chizimuzo Okoli, Tsung-Lan Chu, Ya-Chu Hsiao

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Nursing open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06098924 (The Impacts of Spiritual Health on Depression and Happiness Among Hemodialysis Patients), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06098924 unknown statusnot on this map

The Impacts of Spiritual Health on Depression and Happiness Among Hemodialysis Patients: the Moderator Effects of Life-meaning and Post-trauma Growth

TypeobservationalSponsorChang Gung University of Science and TechnologyRan2023 to 2024Enrolled300ConditionsHemodialysis
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Hsiang-Chun LeeDepartment of Nursing, Chang Gung University of Science and Technology, Division of Nursing Department, New Taipei municipal Tucheng Hospital, New Taipei City, Taiwan, ROC.
Yi-Chien ChiangDepartment of Nursing, Chang Gung University of Science and Technology, Division of Pediatric Hematology and Oncology, Chang Gung Memorial Hospital, Linkou Main Branch, Taoyuan City, Taiwan, ROC.ORCID https://orcid.org/0000-0003-2835-898X
Kun-Hung TsaiDivision of Nephrology, Department of Medicine, Taipei City Hospital, Taipei City, Taiwan, ROC.
Chizimuzo OkoliUniversity of Kentucky College of Nursing, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0002-5674-6253
Tsung-Lan ChuAdministration Center of Quality Management Department, Chang Gung Medical Foundation, Taoyuan City, Taiwan, ROC.ORCID https://orcid.org/0000-0003-0204-4974
Ya-Chu HsiaoAdministration Center of Quality Management Department, Chang Gung Medical Foundation, Taoyuan City, Taiwan, ROC.ORCID https://orcid.org/0000-0002-1672-6266

Funding

Chang Gung Memorial Hospital 501100004824Chang Gung Memorial Hospital BMRP704Chang Gung Memorial Hospital CDRPF1N001National Science and Technology Council NSTC 112-2410-H-255-009
6 · The paper itself

Abstract

aimTo examine the relationships among spirituality, happiness, life attitude and posttraumatic growth in haemodialysis patients, and to test whether life attitude and posttraumatic growth acted as potential mediators in the association between spirituality and happiness.

designA cross-sectional correlational study.

methodsWe recruited 299 maintenance haemodialysis patients from nine dialysis clinics in Taiwan using convenience sampling. Participants completed validated self-report questionnaires measuring spirituality, happiness, life attitude and posttraumatic growth. Pearson's correlation coefficients and mediation analyses using the PROCESS 4.2 macro for SPSS were conducted to test associations and mediating effects.

resultsThe mean age of participants was 60.90 years (SD = 12.39), and the average duration of haemodialysis was 5.32 years (SD = 5.30). Spirituality was significantly positively correlated with happiness, life attitude, and posttraumatic growth (r = 0.571, 0.643 and 0.473; all p < 0.001). Mediation analysis revealed a significant total effect of spirituality on happiness (B = 0.196, 95% CI [0.164, 0.228]) and a direct effect (B = 0.060, 95% CI [0.024, 0.096]). Life attitude and posttraumatic growth significantly mediated this relationship (B = 0.082, 95% CI [0.055, 0.110]) and (B = 0.054, 95% CI [0.035, 0.075]), respectively.

conclusionsSpirituality is associated with higher happiness in haemodialysis patients, and this pattern was consistent with potential indirect pathways via positive life attitudes and promoting posttraumatic growth. These findings offer insight into the psychological mechanisms linking spirituality and well-being in chronically ill patients. IMPACT: Integrating spiritual assessment and tailored interventions into clinical care may be relevant for psychological well-being and overall quality of life in this population. This highlights the importance of addressing spiritual dimensions in chronic care settings. REPORTING

methodStudy methods and results were reported in accordance with the STROBE checklist. PATIENT OR PUBLIC CONTRIBUTION: No patient or public contribution.

trial registrationClinicalTrials.gov: NCT06098924.

Indexed as

HappinessPosttraumatic Growth, PsychologicalRenal DialysisSpiritualityAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPsychological GrowthQuality of LifeSurveys and QuestionnairesTaiwanhaemodialysishappinesslife attitudeposttraumatic growthspirituality

Identifiers

PMID41804610
PMCPMC12972832

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.