ArticleAdvanced materials technologies2025
High-throughput Generation of Collagen Microbeads for Extracellular Vesicle Production and Therapeutic Delivery.
Article in Advanced materials technologies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Additive Manufacturing for Extracellular Vesicle Therapeutics: Engineering Strategies for Production, Isolation, and Delivery.Advanced healthcare materials · 2026Review
- Collagen-Based Microspheres for Biomedical Applications in Drug Delivery and Tissue Engineering.Biomimetics (Basel, Switzerland) · 2026Review
- Engineering Small Extracellular Vesicles for Colon-Targeted Delivery: Microenvironment-Responsive Design, Therapeutic Mechanisms, and Clinical Translation.International journal of nanomedicine · 2026Review
Corrections and comments
- Update of
Authors and funding
7 authors.
Funding
Abstract
Collagen type I, a key component of the extracellular matrix, underpins cellular organization and regeneration but remains challenging to process into scalable, reproducible, and biologically faithful 3D materials. Although several recent platforms have achieved high-throughput collagen microgel fabrication, most rely on chemical modification or rigid process parameters that compromise native collagen structure or limit biological versatility. A scalable yet biologically unmodified system remains lacking. Here, we developed a pressure-tunable microfluidic platform that enables the rapid, high-throughput generation of collagen microbeads with controlled size, fibrillar architecture, and mechanical properties for versatile downstream biofabrication. By adjusting collagen concentrations (0.25-3 mg mL
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.