ArticleCureus2026
Risk Factors for Pseudomyxoma Peritonei in Appendiceal Mucinous Neoplasms: A Single-Center Experience.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
introductionAppendiceal mucinous neoplasms (AMNs) are rare tumors with the potential to progress to pseudomyxoma peritonei (PMP). Identification of prognostic factors may improve surgical management and follow-up strategies.
objectiveThis study aimed to analyze clinicopathological factors associated with the development of PMP in patients with AMNs treated at a tertiary care hospital in Mexico.
methodsA retrospective study was conducted in Hospital Médica Sur, Mexico City, Mexico, including 30 patients with histologically confirmed AMNs between 2018 and 2023. Clinical, surgical, histological, and laboratory variables were analyzed. Bivariate analyses and binary logistic regression models were performed to identify factors associated with the development of PMP.
resultsAppendiceal perforation was the only factor significantly associated with the development of PMP, as the absence of perforation was linked to significantly lower odds of disease (odds ratio (OR): 0.090; 95% confidence interval (CI): 0.010-0.798; p = 0.031). Histological subtypes other than low-grade appendiceal mucinous neoplasm (LAMN) showed a nonsignificant trend toward association (p = 0.076).
conclusionAppendiceal perforation was the main factor associated with the development of PMP in this cohort. Its identification may help guide surgical decision-making and individualized postoperative surveillance strategies.
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