Evidence map›Paper›PMID 41804289›Full record

ArticleInfant mental health journal2026

Family protective service involvement and reduced infant cortical grey matter volume.

Francesca Penner, Banu Ahtam, Yangming Ou, P Ellen Grant, Karlen Lyons-Ruth

Abstract read
In one paragraph

Article in Infant mental health journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francesca PennerDept. of Psychology & Neuroscience, Baylor University, Waco, Texas, USA.ORCID https://orcid.org/0000-0002-8971-790X
Banu AhtamDept. of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Yangming OuDept. of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
P Ellen GrantDept. of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Karlen Lyons-RuthDept. of Psychiatry, Cambridge Health Alliance, Harvard Medical School, Cambridge, Massachusetts, USA.

Funding

Effects of maternal opioid use disorder on neural and behavioral indicators of caregivingF32DA055389 · NIDA · YALE UNIVERSITY · PI PENNER, FRANCESCA · 2022 to 2022
$65k
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD079484Mental Wellness FoundationNIDA NIH HHS F32DA055389
6 · The paper itself

Abstract

Among older children, neglect is linked to reduced cortical grey matter volume, whereas abuse is linked to reduced right amygdala volume. Less is known about whether similar effects of adversity are evident in infancy, a period of particularly rapid brain growth. This study evaluated whether family involvement with child protective services (CPS) was linked to differences in infant brain volumes (whole brain grey matter, cortical grey matter, right and left insular cortex, and right and left amygdala). Participants were recruited in the northeastern United States. Mothers (N = 55) reported on any family involvement with CPS as a parent. Infants completed a brain MRI between 4 and 25 months of age (M

Indexed as

Cerebral CortexChild AbuseChild Protective ServicesGray MatterInsular CortexAmygdalaChild, PreschoolFemaleHumansInfantMagnetic Resonance ImagingMaleOrgan Sizecortical grey mattergrey matter volumeinfancyinsulamaltreatment

Identifiers

PMID41804289
PMCPMC12972846

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.