SynthesisDiabetes, obesity & metabolism2026
Healthcare Resource Utilisation and Cost of Obesity and Related Complications in the United States: A Systematic Literature Review.
Synthesis in Diabetes, obesity & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
aimObesity is an increasingly prevalent, chronic, heterogeneous disease, associated with a variety of obesity-related complications (ORCs). This systematic literature review assessed US healthcare resource utilisation (HCRU) and costs (direct and indirect) for people living with obesity (PwO) or overweight and ORCs.
methodsA search was conducted in January 2024 of studies published from 2019 to present reporting HCRU or costs in adults living with obesity (body mass index [BMI] ≥ 30.0 kg/m
resultsOf 6862 studies identified, 60 met inclusion criteria; 23 reported costs/HCRU in obesity alone and 37 reported obesity and ORCs. In general, PwO with/without ORCs reported higher direct and indirect healthcare costs and HCRU than those without obesity. The highest per-person-per-year healthcare costs were for PwO and chronic kidney disease, heart failure, or type 2 diabetes. PwO and ORCs had up to 23% higher hospitalisation costs and longer hospital lengths of stay (5.2-25.0 vs. 4.9-20.0 days) than those with the same conditions without obesity or with lower BMI. Weight loss resulted in decreases in annual medical expenditure (up to $263 per person per month in people who lost 10%-20% of their bodyweight).
conclusionsThe rising rates of obesity and overweight with/without ORCs create a burden on individuals and the US healthcare system, highlighting a need for more effective prevention and treatments to improve health and reduce associated healthcare costs.
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