Evidence map›Paper›PMID 41804045›Full record

ArticleThe plant genome2026

Genome-wide exploration of bacterial leaf blight resistance and fine mapping of major resistance gene (Bb13) in upland cotton (Gossypium hirsutum L.).

Spoorti S Gandhadmath, Fred M Bourland, S Anjan Gowda, Navin Shrestha, Don C Jones, Kaitlyn Bissonnette, Vasu Kuraparthy

Abstract read
In one paragraph

Article in The plant genome, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Spoorti S GandhadmathDepartment of Crop and Soil Sciences, North Carolina State University, Raleigh, North Carolina, USA.
Fred M BourlandNE Research & Extension Center, University of Arkansas, Keiser, Arkansas, USA.
S Anjan GowdaDepartment of Crop and Soil Sciences, North Carolina State University, Raleigh, North Carolina, USA.
Navin ShresthaDepartment of Crop and Soil Sciences, North Carolina State University, Raleigh, North Carolina, USA.
Don C JonesCotton Incorporated, Cary, North Carolina, USA.
Kaitlyn BissonnetteCotton Incorporated, Cary, North Carolina, USA.
Vasu KuraparthyDepartment of Crop and Soil Sciences, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0002-5913-0403

Funding

Cotton Incorporated 19-952NC Cotton Producers Association 19-796NCUSDA-NIFA
6 · The paper itself

Abstract

Cotton bacterial blight (CBB), caused by Xanthomonas citri subsp. malvacearum (Xcm), continues to pose a significant threat to upland cotton (Gossypium spp.) production across the US Cotton Belt. To elucidate the genetic basis of resistance to race 18 of CBB and identify potential novel resistance sources, we conducted genome-wide association studies (GWASs) using a diversity panel of 661 upland cotton accessions that included elite US germplasm, tropical landraces, and University of Arkansas germplasm releases. GWAS identified a single 3.3 Mb region on chromosome D02 corresponding to the BB13 locus as the primary determinant of race 18 resistance, with no additional major loci detected, indicating Bb13 as the predominant race 18 resistance source in upland cotton. Population genetic analyses suggested uneven distribution of the Bb13 gene across US breeding programs and landraces, likely originating from the African cultivar S295. Linkage mapping in six recombinant inbred line (RIL) populations confirmed segregation of race 18 resistance at the BB13 locus. Fine mapping using PCR allele competitive extension (PACE) markers delimited BB13 locus to a 154.28 kb interval containing nine candidate genes, six of which have homologs implicated in plant disease resistance pathways. The PACE marker CBB16, co-segregating with resistance in both the diversity panel and RIL populations, was identified as a diagnostic marker for Bb13. Local haplotyping further revealed marker groups and haplotypes associated with CBB resistance. Results from this study provide key genomic tools for breeding CBB-resistant cultivars and establish the foundation for positional cloning of the Bb13 gene.

Indexed as

Disease ResistanceGenes, PlantGossypiumPlant DiseasesXanthomonasChromosome MappingGenome-Wide Association StudyPolymorphism, Single Nucleotide

Identifiers

PMID41804045
PMCPMC12972232

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.