Evidence map›Paper›PMID 41803838›Full record

ArticleBMC oral health2026

The property of a root-extended Ti-6Al-4V endocrown utilizing 3D printing for a four-wall defect in endodontically treated molars: An in vitro study.

Yifei Chen, Tingting Song, Kexin Chen, Yichen Xu, Lei Lei, Ran Cheng, Tao Hu

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yifei ChenState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Preventive Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Tingting SongState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Preventive Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Kexin ChenState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Preventive Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Yichen XuState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Preventive Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Lei LeiState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Preventive Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China. leilei@scu.edu.cn.
Ran ChengState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Preventive Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China. chengran@scu.edu.cn.
Tao HuState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Preventive Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China.

Funding

Clinical research project of West China Hospital of Stomatology, Sichuan University LCYJ-MS-202301
6 · The paper itself

Abstract

backgroundSeverely damaged molars pose significant challenges in restorative dentistry. Conventional methods, such as resin composite restorations, often fail to provide sufficient fracture resistance, marginal integrity, and sealing, leading to frequent failures and secondary caries. This study aims to compare the mechanical properties and marginal integrity of 3D-printed Ti-6Al-4V root-extended endocrowns with direct resin composite restorations in molars with 4-wall defects.

methodsForty-two extracted third molars were randomly assigned to a 3D-printed Ti-6Al-4V root-extended endocrown group (n = 21) or a nanohybrid resin composite group (n = 21). All specimens underwent thermocycling. Fracture resistance was evaluated in eight specimens per group using vertical loading. Microleakage was assessed by methylene blue staining, and marginal integrity was evaluated by SEM. Micro-CT was performed on endocrown specimens without visible failure to detect internal microcracks.

resultsThe endocrown group showed a significantly higher fracture resistance than the resin group (4682 ± 981 N vs. 1334 ± 615 N, P < 0.05). No catastrophic failures occurred in the endocrown group, whereas the resin group exhibited multiple failure modes. Lower microleakage scores and fewer marginal defects were observed in the endocrown group (P < 0.05). Micro-CT revealed limited microcracks in two endocrown specimens, and marginal gaps remained within clinically acceptable limits.

conclusionsThe study innovatively designs a 3D-printed Ti-6Al-4V root-extended endocrown, combining the structural advantages of endocrowns and post-core restorations. In our study, the 3D-printed Ti-6Al-4V root-extended endocrowns exhibited markedly enhanced fracture resistance, diminished microleakage, improved marginal integrity in comparison to the direct resin restorations, hence endorsing their application for molars with severe defect.

Indexed as

CrownsMolarPrinting, Three-DimensionalTitaniumTooth, NonvitalAlloysComposite ResinsDental AlloysDental LeakageHumansIn Vitro TechniquesMaterials TestingMicroscopy, Electron, ScanningX-Ray MicrotomographyAlloysComposite ResinsDental AlloysTitaniumtitanium alloy (TiAl6V4)3D printingEndocrownFracture resistanceMarginal adaptionResin restorationsTi-6Al-4V

Identifiers

PMID41803838
PMCPMC13085590

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.